TY - JOUR
T1 - Problems related to the use of sodium hypochlorite in the detoxification of aflatoxin B1
AU - Castegnaro, Marcel
AU - Friesen, Marlin
AU - Michelon, Jocelyne
AU - Walker, Ernest Albert
N1 - Funding Information:
This work has been carried out under NCI Contract No. NO1 CP 45608.
Funding Information:
This research was supported in part by NIOSH, Educational Resources Center Grant OH-07087-04. *present address: Boeing Aerospace Co., Seattle, WA 981 24.
PY - 1981/5/1
Y1 - 1981/5/1
N2 - Sodium hypochlorite solution which has been in use for a long time as a reagent to treat laboratory wastes and equipment contaminated with aflatoxin Bi, has been shown by TLC, HPLC and mass spectrometry to lead to the formation of products which include its carcinogenic 2,3-dichloro derivative. A modification to the method of decontamination using sodium hypochlorite, based on the instability of the 2,3-dichloro derivative in the presence of acetone, is suggested.
AB - Sodium hypochlorite solution which has been in use for a long time as a reagent to treat laboratory wastes and equipment contaminated with aflatoxin Bi, has been shown by TLC, HPLC and mass spectrometry to lead to the formation of products which include its carcinogenic 2,3-dichloro derivative. A modification to the method of decontamination using sodium hypochlorite, based on the instability of the 2,3-dichloro derivative in the presence of acetone, is suggested.
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U2 - 10.1080/15298668191419938
DO - 10.1080/15298668191419938
M3 - Article
AN - SCOPUS:0019505919
SN - 0002-8894
VL - 42
SP - 398
EP - 401
JO - American Industrial Hygiene Association Journal
JF - American Industrial Hygiene Association Journal
IS - 5
ER -