Probabilistic segmentation of brain tumors based on multi-modality magnetic resonance images

Hongmin Cai, Ragini Verma, Yangming Ou, Seung Koo Lee, Elias R. Melhem, Christos Davatzikos

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this paper, multi-modal Magnetic Resonance (MR) images are integrated into a tissue profile that aims at differentiating tumor components, edema and normal tissue. This is achieved by a tissue classification technique that learns the appearance models of different tissue types based on training samples identified by an expert and assigns tissue labels to each voxel. These tissue classifiers produce probabilistic tissue maps reflecting imaging characteristics of tumors and surrounding tissues that may be employed to aid in diagnosis, tumor boundary delineation, surgery and treatment planning. The main contributions of this work are: 1) conventional structural MR modalities are combined with diffusion tensor imaging data to create an integrated multimodality profile for brain tumors, and 2) in addition to the tumor components of enhancing and non-enhancing tumor types, edema is also characterized as a separate class in our framework. Classification performance is tested on 22 diverse tumor cases using cross-validation.

Original languageEnglish (US)
Title of host publication2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings
Pages600-603
Number of pages4
DOIs
Publication statusPublished - 2007
Externally publishedYes
Event2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro; ISBI'07 - Arlington, VA, United States
Duration: Apr 12 2007Apr 15 2007

Other

Other2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro; ISBI'07
CountryUnited States
CityArlington, VA
Period4/12/074/15/07

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Keywords

  • Brain tumors
  • Edema
  • Multimodal MRI data
  • Tissue classification

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Medicine(all)

Cite this

Cai, H., Verma, R., Ou, Y., Lee, S. K., Melhem, E. R., & Davatzikos, C. (2007). Probabilistic segmentation of brain tumors based on multi-modality magnetic resonance images. In 2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings (pp. 600-603). [4193357] https://doi.org/10.1109/ISBI.2007.356923