Probabilistic cost-effectiveness analysis of HIV prevention: Comparing a Bayesian approach with traditional deterministic sensitivity analysis

Ana P. Johnson-Masotti, Purushottam W. Laud, Raymond G. Hoffmann, Matthew J. Hayat, Steven D. Pinkerton

Research output: Contribution to journalArticlepeer-review

Abstract

In cost-effectiveness analysis, the incremental cost-effectiveness ratio is used to measure economic efficiency of a new intervention, relative to an existing one. However, costs and effects are seldom known with certainty. Uncertainty arises from two main sources: uncertainty regarding correct values of intervention-related parameters and uncertainty associated with sampling variation. Recently, attention has focused on Bayesian techniques for quantifying uncertainty. We computed the Bayesian-based 95% credible interval estimates of the incremental cost-effectiveness ratio of several related HIV prevention interventions and compared these results with univariate sensitivity analyses. The conclusions were comparable, even though the probabilistic technique provided additional information.

Original languageEnglish (US)
Pages (from-to)474-502
Number of pages29
JournalEvaluation Review
Volume25
Issue number4
DOIs
StatePublished - Aug 2001

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Social Sciences(all)

Fingerprint

Dive into the research topics of 'Probabilistic cost-effectiveness analysis of HIV prevention: Comparing a Bayesian approach with traditional deterministic sensitivity analysis'. Together they form a unique fingerprint.

Cite this