Pro-inflammatory activated Kupffer cells by lipids induce hepatic NKT cells deficiency through activation-induced cell death

Medicine & Life Sciences

• Kupffer Cells 86%
• Natural Killer T-Cells 86%
• Hepatocytes 60%
• Cell Death 54%
• Lipids 47%
• High Fat Diet 21%
• Antigen Presentation 15%
• Non-alcoholic Fatty Liver Disease 15%
• Cell Count 10%
• In Vitro Techniques 9%
• Antigens 9%
• Cytokines 8%
• Gene Expression 8%
• Toll-Like Receptor 4 8%
• Liver 7%
• Inbred C57BL Mouse 6%
• Innate Immunity 6%
• Fatty Acids 6%
• Necrosis 5%
• Apoptosis 4%
• Phenotype 4%

Agriculture & Biology

• Kupffer cells 100%
• cell death 66%
• hepatocytes 64%
• lipids 38%
• fatty liver 26%
• high fat diet 23%
• antigen presentation 21%
• cells 15%
• cytokines 13%
• Toll-like receptor 4 10%
• antigens 10%
• gene expression 8%
• dietary fat 7%
• innate immunity 7%
• apoptosis 6%
• necrosis 6%
• fatty acids 4%
• phenotype 4%
• mice 4%
• assays 3%
• methodology 1%

Chemical Compounds

• Cell Death 76%
• Lipid 49%
• Antigen 26%
• Fatty Acid 6%
• Surface 2%