Primary vertebral tumors: A review of epidemiologic, histological, and imaging findings, part I: Benign tumors

Alexander E. Ropper, Kevin S. Cahill, John W. Hanna, Edward F. McCarthy, Ziya L. Gokaslan, John H. Chi

Research output: Contribution to journalArticlepeer-review

50 Scopus citations


Primary vertebral tumors, although less common than metastases to the spine, make up a heterogeneous group of neoplasms that can pose diagnostic and treatment challenges. They affect both the adult and the pediatric population and may be benign, locally aggressive, or malignant. An understanding of typical imaging findings will aid in accurate diagnosis and help neurosurgeons appreciate anatomic subtleties that may increase their effective resection. An understanding of the histological similarities and differences between these tumors is imperative for all members of the clinical team caring for these patients. In this first review of 2 parts, we discuss the epidemiological, histological, and imaging features of the most common benign primary vertebral tumors - aneurysmal bone cyst, chondroma and enchondroma, hemangioma, osteoid osteoma, and osteoblastoma - and lesions related to eosinophilic granuloma and fibrous dysplasia. In addition, we discuss the basic management paradigms for each of these diagnoses. In combination with part II of the review, which focuses on locally aggressive and malignant tumors, this article provides a comprehensive review of primary vertebral tumors.

Original languageEnglish (US)
Pages (from-to)1171-1180
Number of pages10
Issue number6
StatePublished - Dec 1 2011


  • Aneurysmal bone cyst
  • Bone tumors
  • Eosinophilic granuloma
  • Hemangioma
  • Osteoid osteoma
  • Primary vertebral tumor
  • Spinal malignancies

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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