TY - JOUR
T1 - Primary vertebral tumors
T2 - A review of epidemiologic, histological, and imaging findings, part I: Benign tumors
AU - Ropper, Alexander E.
AU - Cahill, Kevin S.
AU - Hanna, John W.
AU - McCarthy, Edward F.
AU - Gokaslan, Ziya L.
AU - Chi, John H.
PY - 2011/12/1
Y1 - 2011/12/1
N2 - Primary vertebral tumors, although less common than metastases to the spine, make up a heterogeneous group of neoplasms that can pose diagnostic and treatment challenges. They affect both the adult and the pediatric population and may be benign, locally aggressive, or malignant. An understanding of typical imaging findings will aid in accurate diagnosis and help neurosurgeons appreciate anatomic subtleties that may increase their effective resection. An understanding of the histological similarities and differences between these tumors is imperative for all members of the clinical team caring for these patients. In this first review of 2 parts, we discuss the epidemiological, histological, and imaging features of the most common benign primary vertebral tumors - aneurysmal bone cyst, chondroma and enchondroma, hemangioma, osteoid osteoma, and osteoblastoma - and lesions related to eosinophilic granuloma and fibrous dysplasia. In addition, we discuss the basic management paradigms for each of these diagnoses. In combination with part II of the review, which focuses on locally aggressive and malignant tumors, this article provides a comprehensive review of primary vertebral tumors.
AB - Primary vertebral tumors, although less common than metastases to the spine, make up a heterogeneous group of neoplasms that can pose diagnostic and treatment challenges. They affect both the adult and the pediatric population and may be benign, locally aggressive, or malignant. An understanding of typical imaging findings will aid in accurate diagnosis and help neurosurgeons appreciate anatomic subtleties that may increase their effective resection. An understanding of the histological similarities and differences between these tumors is imperative for all members of the clinical team caring for these patients. In this first review of 2 parts, we discuss the epidemiological, histological, and imaging features of the most common benign primary vertebral tumors - aneurysmal bone cyst, chondroma and enchondroma, hemangioma, osteoid osteoma, and osteoblastoma - and lesions related to eosinophilic granuloma and fibrous dysplasia. In addition, we discuss the basic management paradigms for each of these diagnoses. In combination with part II of the review, which focuses on locally aggressive and malignant tumors, this article provides a comprehensive review of primary vertebral tumors.
KW - Aneurysmal bone cyst
KW - Bone tumors
KW - Eosinophilic granuloma
KW - Hemangioma
KW - Osteoid osteoma
KW - Primary vertebral tumor
KW - Spinal malignancies
UR - http://www.scopus.com/inward/record.url?scp=80955136639&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80955136639&partnerID=8YFLogxK
U2 - 10.1227/NEU.0b013e31822b8107
DO - 10.1227/NEU.0b013e31822b8107
M3 - Article
C2 - 21725252
AN - SCOPUS:80955136639
SN - 0148-396X
VL - 69
SP - 1171
EP - 1180
JO - Neurosurgery
JF - Neurosurgery
IS - 6
ER -