Primary thoracolumbar Ewing's sarcoma presenting as isolated epidural mass

Seref Dogan, Gregory P. Leković, Nicholas Theodore, Eric M. Horn, Jennifer Eschbacher, Harold L. Rekate

Research output: Contribution to journalArticle

Abstract

Background context: Ewing's sarcoma is the most common childhood malignancy of bone, but it rarely occurs as a primary extraosseous epidural tumor. Purpose: To heighten awareness and treatment options of this rare (epidural) presentation of Ewing's sarcoma. Study design: Case report. Methods: Retrospective review. Results: We present a 13-year-old boy with progressive low back and bilateral lower extremity pain and normal neurologic examination. Magnetic resonance imaging showed an extradural tumor in the dorsal epidural space from T11 to L1. He underwent a posterior laminoplasty and gross total resection of tumor; histopathological diagnosis was consistent with Ewing's sarcoma. After surgery, the patient underwent adjuvant chemotherapy and irradiation. At 10 months follow-up, the patient is neurologically intact without evidence of residual disease. Conclusions: Ewing's sarcoma of the epidural space should be considered in the differential diagnosis of epidural mass lesions. Because wide surgical margins cannot be obtained, close follow-up with a low threshold for reoperation is mandatory.

Original languageEnglish (US)
JournalSpine Journal
Volume9
Issue number1
DOIs
StatePublished - Jan 2009
Externally publishedYes

Fingerprint

Ewing's Sarcoma
Epidural Space
Epidural Neoplasms
Neoplasms
Neurologic Examination
Adjuvant Chemotherapy
Reoperation
Lower Extremity
Differential Diagnosis
Magnetic Resonance Imaging
Bone and Bones
Pain
Therapeutics

Keywords

  • Adjuvant therapy
  • Epidural
  • Ewing's sarcoma
  • Extraosseous
  • Spine

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Primary thoracolumbar Ewing's sarcoma presenting as isolated epidural mass. / Dogan, Seref; Leković, Gregory P.; Theodore, Nicholas; Horn, Eric M.; Eschbacher, Jennifer; Rekate, Harold L.

In: Spine Journal, Vol. 9, No. 1, 01.2009.

Research output: Contribution to journalArticle

Dogan, Seref ; Leković, Gregory P. ; Theodore, Nicholas ; Horn, Eric M. ; Eschbacher, Jennifer ; Rekate, Harold L. / Primary thoracolumbar Ewing's sarcoma presenting as isolated epidural mass. In: Spine Journal. 2009 ; Vol. 9, No. 1.
@article{0bf5ca80749a4e968c83e34b13428ac2,
title = "Primary thoracolumbar Ewing's sarcoma presenting as isolated epidural mass",
abstract = "Background context: Ewing's sarcoma is the most common childhood malignancy of bone, but it rarely occurs as a primary extraosseous epidural tumor. Purpose: To heighten awareness and treatment options of this rare (epidural) presentation of Ewing's sarcoma. Study design: Case report. Methods: Retrospective review. Results: We present a 13-year-old boy with progressive low back and bilateral lower extremity pain and normal neurologic examination. Magnetic resonance imaging showed an extradural tumor in the dorsal epidural space from T11 to L1. He underwent a posterior laminoplasty and gross total resection of tumor; histopathological diagnosis was consistent with Ewing's sarcoma. After surgery, the patient underwent adjuvant chemotherapy and irradiation. At 10 months follow-up, the patient is neurologically intact without evidence of residual disease. Conclusions: Ewing's sarcoma of the epidural space should be considered in the differential diagnosis of epidural mass lesions. Because wide surgical margins cannot be obtained, close follow-up with a low threshold for reoperation is mandatory.",
keywords = "Adjuvant therapy, Epidural, Ewing's sarcoma, Extraosseous, Spine",
author = "Seref Dogan and Leković, {Gregory P.} and Nicholas Theodore and Horn, {Eric M.} and Jennifer Eschbacher and Rekate, {Harold L.}",
year = "2009",
month = "1",
doi = "10.1016/j.spinee.2007.11.003",
language = "English (US)",
volume = "9",
journal = "Spine Journal",
issn = "1529-9430",
publisher = "Elsevier Inc.",
number = "1",

}

TY - JOUR

T1 - Primary thoracolumbar Ewing's sarcoma presenting as isolated epidural mass

AU - Dogan, Seref

AU - Leković, Gregory P.

AU - Theodore, Nicholas

AU - Horn, Eric M.

AU - Eschbacher, Jennifer

AU - Rekate, Harold L.

PY - 2009/1

Y1 - 2009/1

N2 - Background context: Ewing's sarcoma is the most common childhood malignancy of bone, but it rarely occurs as a primary extraosseous epidural tumor. Purpose: To heighten awareness and treatment options of this rare (epidural) presentation of Ewing's sarcoma. Study design: Case report. Methods: Retrospective review. Results: We present a 13-year-old boy with progressive low back and bilateral lower extremity pain and normal neurologic examination. Magnetic resonance imaging showed an extradural tumor in the dorsal epidural space from T11 to L1. He underwent a posterior laminoplasty and gross total resection of tumor; histopathological diagnosis was consistent with Ewing's sarcoma. After surgery, the patient underwent adjuvant chemotherapy and irradiation. At 10 months follow-up, the patient is neurologically intact without evidence of residual disease. Conclusions: Ewing's sarcoma of the epidural space should be considered in the differential diagnosis of epidural mass lesions. Because wide surgical margins cannot be obtained, close follow-up with a low threshold for reoperation is mandatory.

AB - Background context: Ewing's sarcoma is the most common childhood malignancy of bone, but it rarely occurs as a primary extraosseous epidural tumor. Purpose: To heighten awareness and treatment options of this rare (epidural) presentation of Ewing's sarcoma. Study design: Case report. Methods: Retrospective review. Results: We present a 13-year-old boy with progressive low back and bilateral lower extremity pain and normal neurologic examination. Magnetic resonance imaging showed an extradural tumor in the dorsal epidural space from T11 to L1. He underwent a posterior laminoplasty and gross total resection of tumor; histopathological diagnosis was consistent with Ewing's sarcoma. After surgery, the patient underwent adjuvant chemotherapy and irradiation. At 10 months follow-up, the patient is neurologically intact without evidence of residual disease. Conclusions: Ewing's sarcoma of the epidural space should be considered in the differential diagnosis of epidural mass lesions. Because wide surgical margins cannot be obtained, close follow-up with a low threshold for reoperation is mandatory.

KW - Adjuvant therapy

KW - Epidural

KW - Ewing's sarcoma

KW - Extraosseous

KW - Spine

UR - http://www.scopus.com/inward/record.url?scp=57849161136&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=57849161136&partnerID=8YFLogxK

U2 - 10.1016/j.spinee.2007.11.003

DO - 10.1016/j.spinee.2007.11.003

M3 - Article

C2 - 18201936

AN - SCOPUS:57849161136

VL - 9

JO - Spine Journal

JF - Spine Journal

SN - 1529-9430

IS - 1

ER -