Primary structure of two nonallelic β-globin chains from DBA/2 mice

M. D. Garrick, R. A. Popp, B. P. Alter

Research output: Contribution to journalArticle

Abstract

The amino acid sequences of the β major and β minor globin chains from DBA/2 mice have been determined. This information is of interest because DBA/2 mice are the strain of origin for most murine erythroleukemia lines. The primary structure of DBA/2 β globins agrees completely with that predicted from the coding properties of BALB/c β globin genes. This identity does not support a rapid evolutionary divergence in inbred mouse strains, at least at these loci in these strains.

Original languageEnglish (US)
Pages (from-to)391-399
Number of pages9
JournalBiochemical Genetics
Volume25
Issue number5-6
DOIs
StatePublished - Jun 1987
Externally publishedYes

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Keywords

  • β major and β minor globin
  • amino acid sequence
  • inbred mice
  • murine erythroleukemia
  • protein evolution

ASJC Scopus subject areas

  • Genetics
  • Biochemistry

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