Primary structure of two nonallelic β-globin chains from DBA/2 mice

M. D. Garrick, R. A. Popp, B. P. Alter

Research output: Contribution to journalArticle

Abstract

The amino acid sequences of the β major and β minor globin chains from DBA/2 mice have been determined. This information is of interest because DBA/2 mice are the strain of origin for most murine erythroleukemia lines. The primary structure of DBA/2 β globins agrees completely with that predicted from the coding properties of BALB/c β globin genes. This identity does not support a rapid evolutionary divergence in inbred mouse strains, at least at these loci in these strains.

Original languageEnglish (US)
Pages (from-to)391-399
Number of pages9
JournalBiochemical Genetics
Volume25
Issue number5-6
DOIs
StatePublished - Jun 1987
Externally publishedYes

Fingerprint

Inbred DBA Mouse
Globins
amino acid
divergence
gene
mice
Leukemia, Erythroblastic, Acute
Inbred Strains Mice
divergent evolution
Amino Acid Sequence
Genes
Amino Acids
amino acid sequences
loci
genes

Keywords

  • β major and β minor globin
  • amino acid sequence
  • inbred mice
  • murine erythroleukemia
  • protein evolution

ASJC Scopus subject areas

  • Genetics
  • Biochemistry

Cite this

Primary structure of two nonallelic β-globin chains from DBA/2 mice. / Garrick, M. D.; Popp, R. A.; Alter, B. P.

In: Biochemical Genetics, Vol. 25, No. 5-6, 06.1987, p. 391-399.

Research output: Contribution to journalArticle

Garrick, M. D. ; Popp, R. A. ; Alter, B. P. / Primary structure of two nonallelic β-globin chains from DBA/2 mice. In: Biochemical Genetics. 1987 ; Vol. 25, No. 5-6. pp. 391-399.
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