Primary small cell neuroendocrine carcinoma of paranasal sinuses

Maliha Khan, Sobia Nizami, Aibek E. Mirrakhimov, Benjamin Maughan, Justin A. Bishop, William Sharfman

Research output: Contribution to journalArticle

Abstract

Small cell neuroendocrine carcinoma of the paranasal sinuses is an extremely rare and aggressive neoplasm. Despite aggressive management, the tumor carries a poor prognosis, with a high risk of local recurrence or distant metastases. The management strategy is based on that for pulmonary small cell cancer and includes platinum-based chemotherapy combined with radiotherapy. We are reporting a case of an 89-year-old female patient diagnosed with small cell carcinoma of right-sided ethmoid and sphenoid sinuses. The tumor was found to have invaded the right orbit and anterior cranial fossa. Metastases to cervical lymph nodes and bone were also found. Due to the extended stage and poor prognosis of the patient, the management plan is palliative chemoradiotherapy.

Original languageEnglish (US)
Article number874719
JournalCase Reports in Medicine
Volume2014
DOIs
StatePublished - 2014

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Neuroendocrine Carcinoma
Small Cell Carcinoma
Paranasal Sinuses
Neoplasms
Anterior Cranial Fossa
Ethmoid Sinus
Neoplasm Metastasis
Sphenoid Sinus
Chemoradiotherapy
Orbit
Platinum
Radiotherapy
Lymph Nodes
Bone and Bones
Recurrence
Drug Therapy
Lung

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Khan, M., Nizami, S., Mirrakhimov, A. E., Maughan, B., Bishop, J. A., & Sharfman, W. (2014). Primary small cell neuroendocrine carcinoma of paranasal sinuses. Case Reports in Medicine, 2014, [874719]. https://doi.org/10.1155/2014/874719

Primary small cell neuroendocrine carcinoma of paranasal sinuses. / Khan, Maliha; Nizami, Sobia; Mirrakhimov, Aibek E.; Maughan, Benjamin; Bishop, Justin A.; Sharfman, William.

In: Case Reports in Medicine, Vol. 2014, 874719, 2014.

Research output: Contribution to journalArticle

Khan, Maliha ; Nizami, Sobia ; Mirrakhimov, Aibek E. ; Maughan, Benjamin ; Bishop, Justin A. ; Sharfman, William. / Primary small cell neuroendocrine carcinoma of paranasal sinuses. In: Case Reports in Medicine. 2014 ; Vol. 2014.
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