Primary low level of high-density lipoprotein cholesterol and risks of coronary heart disease, cardiovascular disease, and death: Results from the multi-ethnic study of atherosclerosis

Haitham M. Ahmed, Michael Miller, Khurram Nasir, John W. McEvoy, David Herrington, Roger S Blumenthal, Michael Blaha

Research output: Contribution to journalArticle

Abstract

Prior studies observing associations between low levels of high-density lipoprotein (HDL) cholesterol and cardiovascular disease (CVD) have often been conducted among persons with metabolic or other lipid abnormalities. In this study, we investigated the association between primary low HDL cholesterol and coronary heart disease (CHD), CVD, and all-cause death after adjustment for confounders in the Multi-Ethnic Study of Atherosclerosis (MESA). Participants who were free of clinical CVD were recruited from 6 US research centers from 2000 to 2002 and followed for a median duration of 10.2 years. We defined "primary low HDL cholesterol" as HDL cholesterol level

Original languageEnglish (US)
Pages (from-to)875-883
Number of pages9
JournalAmerican Journal of Epidemiology
Volume183
Issue number10
DOIs
StatePublished - May 15 2016

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HDL Cholesterol
Coronary Disease
Atherosclerosis
Cardiovascular Diseases
LDL Cholesterol
Cause of Death
Lipids
Research

Keywords

  • cardiovascular disease
  • coronary disease
  • hyperlipidemia
  • lipids
  • lipoproteins

ASJC Scopus subject areas

  • Epidemiology

Cite this

Primary low level of high-density lipoprotein cholesterol and risks of coronary heart disease, cardiovascular disease, and death : Results from the multi-ethnic study of atherosclerosis. / Ahmed, Haitham M.; Miller, Michael; Nasir, Khurram; McEvoy, John W.; Herrington, David; Blumenthal, Roger S; Blaha, Michael.

In: American Journal of Epidemiology, Vol. 183, No. 10, 15.05.2016, p. 875-883.

Research output: Contribution to journalArticle

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