Primary intracerebral small-cell osteosarcoma in an adolescent girl: Report of a case

Eric P. Sipos, Rafael J. Tamargo, Jonathan I. Epstein, Richard B. North

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


A young patient surviving four years after treatment for primary intracerebral small-cell osteosarcoma is reported. This 16-year-old girl presented with headaches, visual disturbance, and papilledema and was found to have a large, heavily calcified mass in the left parietal lobe. A gross total resection of the tumor was performed and pathologic analysis revealed a small-cell osteosarcoma. Thoracic computerized tomography (CT) scans and a complete bone scan showed no other lesions. The patient received adjuvant chemotherapy and radiotherapy. She continues to do well with no evidence of metastases or local recurrence 4 years after her initial presentation. The clinical, radiographic, surgical, pathologic, and immunohistochemical features of this case, along with therapeutic interventions and outcome, are presented.

Original languageEnglish (US)
Pages (from-to)169-174
Number of pages6
JournalJournal of neuro-oncology
Issue number2
StatePublished - Feb 25 1997


  • Brain tumor
  • Central nervous system
  • Chemotherapy
  • Osteosarcoma
  • Radiation therapy

ASJC Scopus subject areas

  • Oncology
  • Neurology
  • Clinical Neurology
  • Cancer Research


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