Primary infertility associated with neuroendocrine tumor (Carcinoid) of the appendix

Brad B. Swelstad, Paul R. Brezina, Clark T. Johnson, Nina Resetkova, Irene Woo, Lisa Kolp

Research output: Contribution to journalArticlepeer-review

Abstract

Neuroendocrine tumors of the appendix (NET-A), formerly called appendiceal carcinoids, are rare tumors of the gastrointestinal tract. Appendiceal tumors have also been associated with infertility. However, in many of these cases, significant abdominal pathology, specifically pseudomyxoma peritonei, was identified during definitive surgical intervention. A 34-year-old nulligravid woman undergoing infertility evaluation presented to an academic tertiary care fertility center. An abnormal mass was identified on hysterosalpingogram and CT confirmed appendiceal mass. Surgical removal of the mass was performed and histopathology was consistent with an NET-A with negative margins extending to the serosa. Two months after surgical intervention, the patient spontaneously conceived pregnancy and subsequently delivered a normal infant. This case exemplifies the importance of careful inspection of radiologic films by the gynecologic physician. Of added interest, this case describes an asymptomatic NET-A associated with primary infertility. To our knowledge, this is the first report of an incidentally indentified NET-A that resulted in primary infertility.

Original languageEnglish (US)
Pages (from-to)152-154
Number of pages3
JournalAsian Pacific Journal of Reproduction
Volume1
Issue number2
DOIs
StatePublished - Jun 1 2012

Keywords

  • Appendiceal
  • Appendiceal carcinoid
  • Carcinoid
  • Infertility

ASJC Scopus subject areas

  • Reproductive Medicine
  • Animal Science and Zoology
  • veterinary(all)
  • Plant Science
  • Obstetrics and Gynecology

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