Primary Immunodeficiency and Rhinosinusitis

Camille Huwyler, Sandra Y. Lin, Jonathan Liang

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations


Refractory rhinosinusitis can be related to comorbid medical conditions, including primary immunodeficiency. Given the prevalence of immunodeficiency, clinicians should have a low threshold to consider these diagnoses. This article reviews primary immunodeficiencies contributing to chronic rhinosinusitis, including a proposed diagnostic work-up and the evidence for treatment in this unique population.

Original languageEnglish (US)
Pages (from-to)233-249
Number of pages17
JournalImmunology and Allergy Clinics of North America
Issue number2
StatePublished - May 2020


  • Antibody deficiency
  • Chronic sinusitis
  • Immune deficiency
  • Immunoglobulin replacement

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


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