Primary Hepatic Cancer

Anan H. Said, Kirti Shetty, Ying Li, Boris Blechacz, Ernest Hawk, Lopa Mishra

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Primary hepatic cancer or hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and the third leading cause of cancer mortality in the United States. It occurs commonly in the setting of cirrhosis and chronic liver disease, particularly viral hepatitis. Radiological studies are the primary modality utilized in the diagnosis of HCC, and serum markers as well as histology have additional roles. HCC is typically diagnosed at an advanced stage of disease, and the median survival time after diagnosis ranges between 6 and 20 months. However, if diagnosed at an early stage, patients suffering from HCC can receive effective curative options including surgical resection, tumor ablation, or liver transplantation. New insights into molecular pathways and targeted therapies carry significant promise for patients with HCC. This edition first published 2013

Original languageEnglish (US)
Title of host publicationHandbook of Gastrointestinal Cancer
PublisherJohn Wiley and Sons
Pages161-181
Number of pages21
ISBN (Print)9780470656242
DOIs
StatePublished - Nov 15 2012

    Fingerprint

Keywords

  • BCLC staging classification
  • Biomarkers
  • Cirrhosis
  • Hepatocellular carcinoma
  • Liver transplantation
  • Molecular therapy
  • Viral hepatitis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Said, A. H., Shetty, K., Li, Y., Blechacz, B., Hawk, E., & Mishra, L. (2012). Primary Hepatic Cancer. In Handbook of Gastrointestinal Cancer (pp. 161-181). John Wiley and Sons. https://doi.org/10.1002/9781118423318.ch7