Primary graft failure after myeloablative allogeneic hematopoietic cell transplantation for hematologic malignancies

R. F. Olsson, B. R. Logan, S. Chaudhury, X. Zhu, G. Akpek, B. J. Bolwell, C. N. Bredeson, C. C. Dvorak, V. Gupta, V. T. Ho, H. M. Lazarus, D. I. Marks, O. T H Ringdén, M. C. Pasquini, J. R. Schriber, Kenneth R Cooke

Research output: Contribution to journalArticle

Abstract

Clinical outcomes after primary graft failure (PGF) remain poor. Here we present a large retrospective analysis (n=23 272) which investigates means to prevent PGF and early detection of patients at high risk. In patients with hematologic malignancies, who underwent their first myeloablative allogeneic hematopoietic cell transplantation, PGF was reported in 1278 (5.5%), and there was a marked difference in PGFs using peripheral blood stem cell compared with bone marrow grafts (2.5 vs 7.3%; P

Original languageEnglish (US)
Pages (from-to)1754-1762
Number of pages9
JournalLeukemia
Volume29
Issue number8
DOIs
StatePublished - Aug 7 2015

Fingerprint

Cell Transplantation
Hematologic Neoplasms
Transplants
Prostaglandins F
Bone Marrow

ASJC Scopus subject areas

  • Hematology
  • Cancer Research
  • Anesthesiology and Pain Medicine

Cite this

Primary graft failure after myeloablative allogeneic hematopoietic cell transplantation for hematologic malignancies. / Olsson, R. F.; Logan, B. R.; Chaudhury, S.; Zhu, X.; Akpek, G.; Bolwell, B. J.; Bredeson, C. N.; Dvorak, C. C.; Gupta, V.; Ho, V. T.; Lazarus, H. M.; Marks, D. I.; Ringdén, O. T H; Pasquini, M. C.; Schriber, J. R.; Cooke, Kenneth R.

In: Leukemia, Vol. 29, No. 8, 07.08.2015, p. 1754-1762.

Research output: Contribution to journalArticle

Olsson, RF, Logan, BR, Chaudhury, S, Zhu, X, Akpek, G, Bolwell, BJ, Bredeson, CN, Dvorak, CC, Gupta, V, Ho, VT, Lazarus, HM, Marks, DI, Ringdén, OTH, Pasquini, MC, Schriber, JR & Cooke, KR 2015, 'Primary graft failure after myeloablative allogeneic hematopoietic cell transplantation for hematologic malignancies', Leukemia, vol. 29, no. 8, pp. 1754-1762. https://doi.org/10.1038/leu.2015.75
Olsson, R. F. ; Logan, B. R. ; Chaudhury, S. ; Zhu, X. ; Akpek, G. ; Bolwell, B. J. ; Bredeson, C. N. ; Dvorak, C. C. ; Gupta, V. ; Ho, V. T. ; Lazarus, H. M. ; Marks, D. I. ; Ringdén, O. T H ; Pasquini, M. C. ; Schriber, J. R. ; Cooke, Kenneth R. / Primary graft failure after myeloablative allogeneic hematopoietic cell transplantation for hematologic malignancies. In: Leukemia. 2015 ; Vol. 29, No. 8. pp. 1754-1762.
@article{66f893a91f0a452eac9019e015efe087,
title = "Primary graft failure after myeloablative allogeneic hematopoietic cell transplantation for hematologic malignancies",
abstract = "Clinical outcomes after primary graft failure (PGF) remain poor. Here we present a large retrospective analysis (n=23 272) which investigates means to prevent PGF and early detection of patients at high risk. In patients with hematologic malignancies, who underwent their first myeloablative allogeneic hematopoietic cell transplantation, PGF was reported in 1278 (5.5{\%}), and there was a marked difference in PGFs using peripheral blood stem cell compared with bone marrow grafts (2.5 vs 7.3{\%}; P",
author = "Olsson, {R. F.} and Logan, {B. R.} and S. Chaudhury and X. Zhu and G. Akpek and Bolwell, {B. J.} and Bredeson, {C. N.} and Dvorak, {C. C.} and V. Gupta and Ho, {V. T.} and Lazarus, {H. M.} and Marks, {D. I.} and Ringd{\'e}n, {O. T H} and Pasquini, {M. C.} and Schriber, {J. R.} and Cooke, {Kenneth R}",
year = "2015",
month = "8",
day = "7",
doi = "10.1038/leu.2015.75",
language = "English (US)",
volume = "29",
pages = "1754--1762",
journal = "Leukemia",
issn = "0887-6924",
publisher = "Nature Publishing Group",
number = "8",

}

TY - JOUR

T1 - Primary graft failure after myeloablative allogeneic hematopoietic cell transplantation for hematologic malignancies

AU - Olsson, R. F.

AU - Logan, B. R.

AU - Chaudhury, S.

AU - Zhu, X.

AU - Akpek, G.

AU - Bolwell, B. J.

AU - Bredeson, C. N.

AU - Dvorak, C. C.

AU - Gupta, V.

AU - Ho, V. T.

AU - Lazarus, H. M.

AU - Marks, D. I.

AU - Ringdén, O. T H

AU - Pasquini, M. C.

AU - Schriber, J. R.

AU - Cooke, Kenneth R

PY - 2015/8/7

Y1 - 2015/8/7

N2 - Clinical outcomes after primary graft failure (PGF) remain poor. Here we present a large retrospective analysis (n=23 272) which investigates means to prevent PGF and early detection of patients at high risk. In patients with hematologic malignancies, who underwent their first myeloablative allogeneic hematopoietic cell transplantation, PGF was reported in 1278 (5.5%), and there was a marked difference in PGFs using peripheral blood stem cell compared with bone marrow grafts (2.5 vs 7.3%; P

AB - Clinical outcomes after primary graft failure (PGF) remain poor. Here we present a large retrospective analysis (n=23 272) which investigates means to prevent PGF and early detection of patients at high risk. In patients with hematologic malignancies, who underwent their first myeloablative allogeneic hematopoietic cell transplantation, PGF was reported in 1278 (5.5%), and there was a marked difference in PGFs using peripheral blood stem cell compared with bone marrow grafts (2.5 vs 7.3%; P

UR - http://www.scopus.com/inward/record.url?scp=84938991869&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84938991869&partnerID=8YFLogxK

U2 - 10.1038/leu.2015.75

DO - 10.1038/leu.2015.75

M3 - Article

C2 - 25772027

AN - SCOPUS:84938991869

VL - 29

SP - 1754

EP - 1762

JO - Leukemia

JF - Leukemia

SN - 0887-6924

IS - 8

ER -