Abstract
Background Soft tissue sarcomas (STS) are rare and are commonly excised outside of a sarcoma center without appropriate preoperative planning. Studies have shown varying results in survival and outcome when comparing patients undergoing re-excision to patients undergoing a single, planned excision. Methods This retrospective study evaluated 278 patients treated for STS of the extremities between January 2000 and July 2006. One hundred seventy-two patients had a primary excision while 106 patients had a sarcoma re-excised. Survival curves for disease-free survival, metastasis-free survival, and local recurrence-free survival were calculated using competing risk analysis for both groups. Results After adjusting for high-risk variables, our results indicate that re-excision is a proxy for smaller, low-grade tumors which tend to have a better survival profile. Death due to sarcoma and distant metastases were correlated with high-grade and large tumors. The presence of positive microscopic margins was the strongest predictor of local recurrence (P
Original language | English (US) |
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Pages (from-to) | 662-667 |
Number of pages | 6 |
Journal | Journal of Surgical Oncology |
Volume | 105 |
Issue number | 7 |
DOIs | |
State | Published - Jun 1 2012 |
Externally published | Yes |
Keywords
- local recurrence
- metastasis
- planned excision
- re-excision
- soft tissue sarcoma
- survival
ASJC Scopus subject areas
- Surgery
- Oncology