Primary antifungal prophylaxis in hematopoietic stem cell transplant recipients

Clinical implications of recent studies

Research output: Contribution to journalArticle

Abstract

Clinicians should consider using new mold-active azole drugs for prophylaxis instead of fluconazole in allogeneic hematopoietic stem cell transplant recipients that have high risks due to prolonged neutropenia and severe graft vs. host disease. More investigations are needed to support other preventive strategies that utilize diagnostic tests and aerosolized delivery of amphotericin B formulations.

Original languageEnglish (US)
Pages (from-to)409-414
Number of pages6
JournalCurrent Opinion in Infectious Diseases
Volume21
Issue number4
DOIs
StatePublished - Aug 2008
Externally publishedYes

Fingerprint

Hematopoietic Stem Cells
Transplants
Azoles
Fluconazole
Amphotericin B
Neutropenia
Routine Diagnostic Tests
Fungi
Pharmaceutical Preparations
Transplant Recipients

Keywords

  • Invasive fungal infections
  • Prophylaxis
  • Transplantation

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases
  • Immunology

Cite this

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abstract = "Clinicians should consider using new mold-active azole drugs for prophylaxis instead of fluconazole in allogeneic hematopoietic stem cell transplant recipients that have high risks due to prolonged neutropenia and severe graft vs. host disease. More investigations are needed to support other preventive strategies that utilize diagnostic tests and aerosolized delivery of amphotericin B formulations.",
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