Prevalence of virulence genes and cytolethal distending toxin production in Campylobacter jejuni isolates from diarrheal patients in Bangladesh

Kaisar A. Talukder, Mohammad Aslam, Zhahirul Islam, Ishrat J. Azmi, Dilip K. Dutta, Sabir Hossain, Alam Nur-E-Kamal, Gopinath B. Nair, Alejandro Cravioto, David A. Sack, Hubert P. Endtz

Research output: Contribution to journalArticle

Abstract

From 300 stool samples, 58 Campylobacter strains were isolated by standard microbiological and biochemical methods. Of these, 40 strains were identified as Campylobacter jejuni and 5 as Campylobacter coli. The presence of flaA (100%), cadF (100%), racR (100%), dnaJ (100%), pldA (100%), ciaB (95%), virB11 (0%), ceuE (82.5%), cdtA (97.5%), cdtB (97.5%), cdtC (97.5%), and wlaN (7.5%) genes was detected in C. jejuni by PCR. All C. jejuni strains but one produced cytolethal distending toxin in a HeLa cell assay.

Original languageEnglish (US)
Pages (from-to)1485-1488
Number of pages4
JournalJournal of Clinical Microbiology
Volume46
Issue number4
DOIs
StatePublished - Apr 2008
Externally publishedYes

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Campylobacter jejuni
Bangladesh
Virulence
Campylobacter coli
Genes
Campylobacter
HeLa Cells
Polymerase Chain Reaction
cytolethal distending toxin

ASJC Scopus subject areas

  • Microbiology (medical)
  • Microbiology

Cite this

Prevalence of virulence genes and cytolethal distending toxin production in Campylobacter jejuni isolates from diarrheal patients in Bangladesh. / Talukder, Kaisar A.; Aslam, Mohammad; Islam, Zhahirul; Azmi, Ishrat J.; Dutta, Dilip K.; Hossain, Sabir; Nur-E-Kamal, Alam; Nair, Gopinath B.; Cravioto, Alejandro; Sack, David A.; Endtz, Hubert P.

In: Journal of Clinical Microbiology, Vol. 46, No. 4, 04.2008, p. 1485-1488.

Research output: Contribution to journalArticle

Talukder, KA, Aslam, M, Islam, Z, Azmi, IJ, Dutta, DK, Hossain, S, Nur-E-Kamal, A, Nair, GB, Cravioto, A, Sack, DA & Endtz, HP 2008, 'Prevalence of virulence genes and cytolethal distending toxin production in Campylobacter jejuni isolates from diarrheal patients in Bangladesh', Journal of Clinical Microbiology, vol. 46, no. 4, pp. 1485-1488. https://doi.org/10.1128/JCM.01912-07
Talukder, Kaisar A. ; Aslam, Mohammad ; Islam, Zhahirul ; Azmi, Ishrat J. ; Dutta, Dilip K. ; Hossain, Sabir ; Nur-E-Kamal, Alam ; Nair, Gopinath B. ; Cravioto, Alejandro ; Sack, David A. ; Endtz, Hubert P. / Prevalence of virulence genes and cytolethal distending toxin production in Campylobacter jejuni isolates from diarrheal patients in Bangladesh. In: Journal of Clinical Microbiology. 2008 ; Vol. 46, No. 4. pp. 1485-1488.
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