Prevalence of Plateau Iris in Primary Angle Closure Suspects. An Ultrasound Biomicroscopy Study

Rajesh S. Kumar, Mani Baskaran, Paul T K Chew, David S Friedman, Swati Handa, Raghavan Lavanya, Lisandro M. Sakata, Hon Tym Wong, Tin Aung

Research output: Contribution to journalArticle

Abstract

Purpose: To determine the prevalence of plateau iris in a cohort of primary angle closure suspects (PACSs) using ultrasound biomicroscopy (UBM). Design: Cross-sectional observational study. Participants: Subjects over the age of 50 years diagnosed as PACSs. Intervention: Subjects were randomized to undergo laser peripheral iridotomy (LPI) in one eye. Ultrasound biomicroscopy was performed before and a week after LPI. Main Outcome Measures: Ultrasound biomicroscopy images were qualitatively assessed using standardized criteria. Plateau iris was defined in a quadrant by the presence of an anteriorly directed ciliary body, an absent ciliary sulcus, a steep iris root from its point of insertion followed by a downward angulation from the corneoscleral wall, presence of a central flat iris plane, and irido-angle contact. At least 2 quadrants had to fulfil the above criteria for an eye to be defined as plateau iris. Results: Two hundred five subjects were enrolled; UBM images of 167 subjects were available for analysis. Plateau iris was found in 54 of 167 (32.3%) PACS eyes after LPI. Quadrantwise analysis showed that 44 of 167 (26.3%) eyes had plateau iris in 1 quadrant, 36 (21.5%) in 2 quadrants, 16 (9.5%) in 3 quadrants, and 2 (1.2%) in all 4 quadrants. Plateau iris was most commonly observed in the superior and inferior quadrants. Conclusions: Using standardized UBM criteria, plateau iris was found in about a third of PACS eyes after LPI. Prospective longitudinal studies are required to determine the clinical significance of this finding for the management of PACSs.

Original languageEnglish (US)
Pages (from-to)430-434
Number of pages5
JournalOphthalmology
Volume115
Issue number3
DOIs
StatePublished - Mar 2008

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Acoustic Microscopy
Iris
Lasers
Ciliary Body
Observational Studies
Longitudinal Studies
Cross-Sectional Studies
Outcome Assessment (Health Care)
Prospective Studies

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Prevalence of Plateau Iris in Primary Angle Closure Suspects. An Ultrasound Biomicroscopy Study. / Kumar, Rajesh S.; Baskaran, Mani; Chew, Paul T K; Friedman, David S; Handa, Swati; Lavanya, Raghavan; Sakata, Lisandro M.; Wong, Hon Tym; Aung, Tin.

In: Ophthalmology, Vol. 115, No. 3, 03.2008, p. 430-434.

Research output: Contribution to journalArticle

Kumar, RS, Baskaran, M, Chew, PTK, Friedman, DS, Handa, S, Lavanya, R, Sakata, LM, Wong, HT & Aung, T 2008, 'Prevalence of Plateau Iris in Primary Angle Closure Suspects. An Ultrasound Biomicroscopy Study', Ophthalmology, vol. 115, no. 3, pp. 430-434. https://doi.org/10.1016/j.ophtha.2007.07.026
Kumar, Rajesh S. ; Baskaran, Mani ; Chew, Paul T K ; Friedman, David S ; Handa, Swati ; Lavanya, Raghavan ; Sakata, Lisandro M. ; Wong, Hon Tym ; Aung, Tin. / Prevalence of Plateau Iris in Primary Angle Closure Suspects. An Ultrasound Biomicroscopy Study. In: Ophthalmology. 2008 ; Vol. 115, No. 3. pp. 430-434.
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AU - Friedman, David S

AU - Handa, Swati

AU - Lavanya, Raghavan

AU - Sakata, Lisandro M.

AU - Wong, Hon Tym

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N2 - Purpose: To determine the prevalence of plateau iris in a cohort of primary angle closure suspects (PACSs) using ultrasound biomicroscopy (UBM). Design: Cross-sectional observational study. Participants: Subjects over the age of 50 years diagnosed as PACSs. Intervention: Subjects were randomized to undergo laser peripheral iridotomy (LPI) in one eye. Ultrasound biomicroscopy was performed before and a week after LPI. Main Outcome Measures: Ultrasound biomicroscopy images were qualitatively assessed using standardized criteria. Plateau iris was defined in a quadrant by the presence of an anteriorly directed ciliary body, an absent ciliary sulcus, a steep iris root from its point of insertion followed by a downward angulation from the corneoscleral wall, presence of a central flat iris plane, and irido-angle contact. At least 2 quadrants had to fulfil the above criteria for an eye to be defined as plateau iris. Results: Two hundred five subjects were enrolled; UBM images of 167 subjects were available for analysis. Plateau iris was found in 54 of 167 (32.3%) PACS eyes after LPI. Quadrantwise analysis showed that 44 of 167 (26.3%) eyes had plateau iris in 1 quadrant, 36 (21.5%) in 2 quadrants, 16 (9.5%) in 3 quadrants, and 2 (1.2%) in all 4 quadrants. Plateau iris was most commonly observed in the superior and inferior quadrants. Conclusions: Using standardized UBM criteria, plateau iris was found in about a third of PACS eyes after LPI. Prospective longitudinal studies are required to determine the clinical significance of this finding for the management of PACSs.

AB - Purpose: To determine the prevalence of plateau iris in a cohort of primary angle closure suspects (PACSs) using ultrasound biomicroscopy (UBM). Design: Cross-sectional observational study. Participants: Subjects over the age of 50 years diagnosed as PACSs. Intervention: Subjects were randomized to undergo laser peripheral iridotomy (LPI) in one eye. Ultrasound biomicroscopy was performed before and a week after LPI. Main Outcome Measures: Ultrasound biomicroscopy images were qualitatively assessed using standardized criteria. Plateau iris was defined in a quadrant by the presence of an anteriorly directed ciliary body, an absent ciliary sulcus, a steep iris root from its point of insertion followed by a downward angulation from the corneoscleral wall, presence of a central flat iris plane, and irido-angle contact. At least 2 quadrants had to fulfil the above criteria for an eye to be defined as plateau iris. Results: Two hundred five subjects were enrolled; UBM images of 167 subjects were available for analysis. Plateau iris was found in 54 of 167 (32.3%) PACS eyes after LPI. Quadrantwise analysis showed that 44 of 167 (26.3%) eyes had plateau iris in 1 quadrant, 36 (21.5%) in 2 quadrants, 16 (9.5%) in 3 quadrants, and 2 (1.2%) in all 4 quadrants. Plateau iris was most commonly observed in the superior and inferior quadrants. Conclusions: Using standardized UBM criteria, plateau iris was found in about a third of PACS eyes after LPI. Prospective longitudinal studies are required to determine the clinical significance of this finding for the management of PACSs.

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