Prevalence of map-dot-fingerprint changes in the cornea

T. P. Werblin, L. W. Hirst, W. J. Stark, I. H. Maumenee

Research output: Contribution to journalArticle

Abstract

Map-dot-fingerprint basement-membrane abnormalities of the cornea are common in the general population, affecting as many as 76% of persons over 50 and 42% of persons of all ages. The prevalence of this condition in the general population is not significantly different from that found in families of patients with recurrent corneal erosions and map-dot-fingerprint corneal changes. Despite this extremely high prevalence of basement-membrane changes is quite rare, suggesting that these 2 entities are possibly not related. Although previous observers have suggested an autosomal dominant mode of inheritance of these basement-membrane changes, our data raise the possibility that map-dot-fingerprint basement-membrane changes represent an age-dependent, degenerative condition of the cornea. We were unable, however, to prove either hypothesis.

Original languageEnglish (US)
Pages (from-to)401-409
Number of pages9
JournalBritish Journal of Ophthalmology
Volume65
Issue number6
DOIs
StatePublished - 1981

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Fingerprint Dive into the research topics of 'Prevalence of map-dot-fingerprint changes in the cornea'. Together they form a unique fingerprint.

  • Cite this

    Werblin, T. P., Hirst, L. W., Stark, W. J., & Maumenee, I. H. (1981). Prevalence of map-dot-fingerprint changes in the cornea. British Journal of Ophthalmology, 65(6), 401-409. https://doi.org/10.1136/bjo.65.6.401