Prevalence of latex-specific IgE antibodies in hospital personnel

Ronald G. Kaczmarek, Barbara G. Silverman, Thomas P. Gross, Robert G Hamilton, Eileen Kessler, J. Thomas Arrowsmith-Lowe, Roscoe M. Moore

Research output: Contribution to journalArticle

Abstract

Background: Rubber latex hypersensitivity is an important concern for health care workers. Purpose: The Center for Devices and Radiological Health, in collaboration with the Consumer Product Safety Commission, conducted a multicenter study of the prevalence of latex-specific IgE antibodies among United States hospital personnel. Materials and Methods: Nine hospitals participated in the cross-sectional study. A total of 504 hospital personnel completed questionnaires that provided an array of demographic, occupational, and clinical information, including a history, if any, of allergies and the use of latex and nonlatex gloves. More than three-quarters (76.5%) of the participants were tested for total IgE and latex specific IgE. Results: A total of 21 (5.5%, 95% CI = 3%-7%) of the tested participants were positive for the presence of latex specific IgE antibodies, defined as a latex IgE level of ≥0.6 ng/mL. Latex specific IgE antibodies were more prevalent in participants who reported tachycardia, palpitations, flushing, or wheezing associated with latex gloves (Odds Ratio = 10.2, 95% CI = 3.7-28.6). Conclusion: The study's results suggest that the prevalence of latex-specific IgE antibodies among hospital personnel is appreciable and these personnel and their health care providers should be aware of this entity.

Original languageEnglish (US)
Pages (from-to)51-56
Number of pages6
JournalAnnals of Allergy, Asthma and Immunology
Volume76
Issue number1
StatePublished - Jan 1996
Externally publishedYes

Fingerprint

Hospital Personnel
Latex
Immunoglobulin E
Antibodies
Latex Hypersensitivity
Radiologic Health
Consumer Product Safety
State Hospitals
Rubber
Respiratory Sounds
Tachycardia
Health Personnel
Multicenter Studies
Cross-Sectional Studies
History
Odds Ratio
Demography
Delivery of Health Care
Equipment and Supplies

ASJC Scopus subject areas

  • Immunology and Allergy

Cite this

Kaczmarek, R. G., Silverman, B. G., Gross, T. P., Hamilton, R. G., Kessler, E., Arrowsmith-Lowe, J. T., & Moore, R. M. (1996). Prevalence of latex-specific IgE antibodies in hospital personnel. Annals of Allergy, Asthma and Immunology, 76(1), 51-56.

Prevalence of latex-specific IgE antibodies in hospital personnel. / Kaczmarek, Ronald G.; Silverman, Barbara G.; Gross, Thomas P.; Hamilton, Robert G; Kessler, Eileen; Arrowsmith-Lowe, J. Thomas; Moore, Roscoe M.

In: Annals of Allergy, Asthma and Immunology, Vol. 76, No. 1, 01.1996, p. 51-56.

Research output: Contribution to journalArticle

Kaczmarek, RG, Silverman, BG, Gross, TP, Hamilton, RG, Kessler, E, Arrowsmith-Lowe, JT & Moore, RM 1996, 'Prevalence of latex-specific IgE antibodies in hospital personnel', Annals of Allergy, Asthma and Immunology, vol. 76, no. 1, pp. 51-56.
Kaczmarek RG, Silverman BG, Gross TP, Hamilton RG, Kessler E, Arrowsmith-Lowe JT et al. Prevalence of latex-specific IgE antibodies in hospital personnel. Annals of Allergy, Asthma and Immunology. 1996 Jan;76(1):51-56.
Kaczmarek, Ronald G. ; Silverman, Barbara G. ; Gross, Thomas P. ; Hamilton, Robert G ; Kessler, Eileen ; Arrowsmith-Lowe, J. Thomas ; Moore, Roscoe M. / Prevalence of latex-specific IgE antibodies in hospital personnel. In: Annals of Allergy, Asthma and Immunology. 1996 ; Vol. 76, No. 1. pp. 51-56.
@article{58507c7f9f7e439f8106aac9856a221f,
title = "Prevalence of latex-specific IgE antibodies in hospital personnel",
abstract = "Background: Rubber latex hypersensitivity is an important concern for health care workers. Purpose: The Center for Devices and Radiological Health, in collaboration with the Consumer Product Safety Commission, conducted a multicenter study of the prevalence of latex-specific IgE antibodies among United States hospital personnel. Materials and Methods: Nine hospitals participated in the cross-sectional study. A total of 504 hospital personnel completed questionnaires that provided an array of demographic, occupational, and clinical information, including a history, if any, of allergies and the use of latex and nonlatex gloves. More than three-quarters (76.5{\%}) of the participants were tested for total IgE and latex specific IgE. Results: A total of 21 (5.5{\%}, 95{\%} CI = 3{\%}-7{\%}) of the tested participants were positive for the presence of latex specific IgE antibodies, defined as a latex IgE level of ≥0.6 ng/mL. Latex specific IgE antibodies were more prevalent in participants who reported tachycardia, palpitations, flushing, or wheezing associated with latex gloves (Odds Ratio = 10.2, 95{\%} CI = 3.7-28.6). Conclusion: The study's results suggest that the prevalence of latex-specific IgE antibodies among hospital personnel is appreciable and these personnel and their health care providers should be aware of this entity.",
author = "Kaczmarek, {Ronald G.} and Silverman, {Barbara G.} and Gross, {Thomas P.} and Hamilton, {Robert G} and Eileen Kessler and Arrowsmith-Lowe, {J. Thomas} and Moore, {Roscoe M.}",
year = "1996",
month = "1",
language = "English (US)",
volume = "76",
pages = "51--56",
journal = "Annals of Allergy, Asthma and Immunology",
issn = "1081-1206",
publisher = "American College of Allergy, Asthma and Immunology",
number = "1",

}

TY - JOUR

T1 - Prevalence of latex-specific IgE antibodies in hospital personnel

AU - Kaczmarek, Ronald G.

AU - Silverman, Barbara G.

AU - Gross, Thomas P.

AU - Hamilton, Robert G

AU - Kessler, Eileen

AU - Arrowsmith-Lowe, J. Thomas

AU - Moore, Roscoe M.

PY - 1996/1

Y1 - 1996/1

N2 - Background: Rubber latex hypersensitivity is an important concern for health care workers. Purpose: The Center for Devices and Radiological Health, in collaboration with the Consumer Product Safety Commission, conducted a multicenter study of the prevalence of latex-specific IgE antibodies among United States hospital personnel. Materials and Methods: Nine hospitals participated in the cross-sectional study. A total of 504 hospital personnel completed questionnaires that provided an array of demographic, occupational, and clinical information, including a history, if any, of allergies and the use of latex and nonlatex gloves. More than three-quarters (76.5%) of the participants were tested for total IgE and latex specific IgE. Results: A total of 21 (5.5%, 95% CI = 3%-7%) of the tested participants were positive for the presence of latex specific IgE antibodies, defined as a latex IgE level of ≥0.6 ng/mL. Latex specific IgE antibodies were more prevalent in participants who reported tachycardia, palpitations, flushing, or wheezing associated with latex gloves (Odds Ratio = 10.2, 95% CI = 3.7-28.6). Conclusion: The study's results suggest that the prevalence of latex-specific IgE antibodies among hospital personnel is appreciable and these personnel and their health care providers should be aware of this entity.

AB - Background: Rubber latex hypersensitivity is an important concern for health care workers. Purpose: The Center for Devices and Radiological Health, in collaboration with the Consumer Product Safety Commission, conducted a multicenter study of the prevalence of latex-specific IgE antibodies among United States hospital personnel. Materials and Methods: Nine hospitals participated in the cross-sectional study. A total of 504 hospital personnel completed questionnaires that provided an array of demographic, occupational, and clinical information, including a history, if any, of allergies and the use of latex and nonlatex gloves. More than three-quarters (76.5%) of the participants were tested for total IgE and latex specific IgE. Results: A total of 21 (5.5%, 95% CI = 3%-7%) of the tested participants were positive for the presence of latex specific IgE antibodies, defined as a latex IgE level of ≥0.6 ng/mL. Latex specific IgE antibodies were more prevalent in participants who reported tachycardia, palpitations, flushing, or wheezing associated with latex gloves (Odds Ratio = 10.2, 95% CI = 3.7-28.6). Conclusion: The study's results suggest that the prevalence of latex-specific IgE antibodies among hospital personnel is appreciable and these personnel and their health care providers should be aware of this entity.

UR - http://www.scopus.com/inward/record.url?scp=0030024704&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030024704&partnerID=8YFLogxK

M3 - Article

C2 - 8564628

AN - SCOPUS:0030024704

VL - 76

SP - 51

EP - 56

JO - Annals of Allergy, Asthma and Immunology

JF - Annals of Allergy, Asthma and Immunology

SN - 1081-1206

IS - 1

ER -