Abstract
Objective: The purpose of this study was to evaluate the prevalence of hepatitis B and hepatitis C virus co-infection among pregnant women who are infected by human immunodeficiency virus and who attend an obstetric complications prenatal clinic. Study design: A de-identified research obstetric human immunodeficiency virus database was reviewed regarding patient demographic characteristics, risk factors for infection, history of sexually transmitted diseases, and initial CD4 count. Results: Four hundred fifty-five women who are infected with human immunodeficiency virus with 572 pregnancies were delivered over 11 years. The overall prevalence of human immunodeficiency virus and hepatitis B or C virus co-infection in our population was 6.3%. More specifically, 1.5% was co-infected with hepatitis B virus, and 4.9% was co-infected with hepatitis C virus. Patients with hepatitis virus were more likely to use intravenous drugs (52% vs 18%; P < .01) and alcohol (38% vs 5%; P < .01). Co-infected patients were older (28 vs 25.6 years; P = .04), but there were no racial differences. Median baseline CD4 counts in hepatitis B virus co-infected patients were significantly lower (310 cells/mm3) than those in either hepatitis C virus co-infected patients (453 cells/mm 3) or patients who were not co-infected with human immunodeficiency virus (414 cells/mm3). Conclusion: One of 16 pregnant women who were infected with human immunodeficiency virus was co-infected with hepatitis B or hepatitis C virus. Hepatitis B co-infections appear to be associated with more compromised immune status in our cohort.
Original language | English (US) |
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Pages (from-to) | 1270-1273 |
Number of pages | 4 |
Journal | American journal of obstetrics and gynecology |
Volume | 193 |
Issue number | 3 SUPPL. |
DOIs | |
State | Published - Sep 2005 |
Externally published | Yes |
Keywords
- Co-infection
- Hepatitis B virus
- Hepatitis C virus
- Human immunodeficiency virus
- Pregnancy
ASJC Scopus subject areas
- Obstetrics and Gynecology