Prevalence of G2P[4] and G12P[6] rotavirus, Bangladesh

Mustafizur Rahman, Rasheda Sultana, Giasuddin Ahmed, Sharifun Nahar, Zahid M. Hassan, Farjana Saiada, Goutam Podder, Abu S G Faruque, A. K. Siddique, David A. Sack, Jelle Matthijnssens, Marc Van Ranst, Tasnim Azim

Research output: Contribution to journalArticle

Abstract

Approximately 20,000 stool specimens from patients with diarrhea visiting 1 urban and 1 rural hospital in Bangladesh during January 2001-May 2006 were tested for group A rotavirus antigen, and 4,712 (24.0%) were positive. G and P genotyping was performed on a subset of 10% of the positive samples (n = 471). During the 2001-2005 rotavirus seasons, G1P[8] (36.4%) and G9P[8] (27.7%) were the dominant strains, but G2[4] and G12P[6] were present in 15.4% and 3.1% of the rotavirus-positive patients, respectively. During the 2005-06 rotavirus season, G2P[4] (43.2%) appeared as the most prevalent strain, and G12P[6] became a more prevalent strain (11.1%) during this season. Because recently licensed rotavirus vaccines include only the P[8] specificity, it is unknown how the vaccines will perform in settings where non-P[8] types are prevalent.

Original languageEnglish (US)
Pages (from-to)18-24
Number of pages7
JournalEmerging Infectious Diseases
Volume13
Issue number1
StatePublished - Jan 2007
Externally publishedYes

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Bangladesh
Rotavirus
Rotavirus Vaccines
Rural Hospitals
Diarrhea
Vaccines
Antigens

ASJC Scopus subject areas

  • Microbiology (medical)

Cite this

Rahman, M., Sultana, R., Ahmed, G., Nahar, S., Hassan, Z. M., Saiada, F., ... Azim, T. (2007). Prevalence of G2P[4] and G12P[6] rotavirus, Bangladesh. Emerging Infectious Diseases, 13(1), 18-24.

Prevalence of G2P[4] and G12P[6] rotavirus, Bangladesh. / Rahman, Mustafizur; Sultana, Rasheda; Ahmed, Giasuddin; Nahar, Sharifun; Hassan, Zahid M.; Saiada, Farjana; Podder, Goutam; Faruque, Abu S G; Siddique, A. K.; Sack, David A.; Matthijnssens, Jelle; Van Ranst, Marc; Azim, Tasnim.

In: Emerging Infectious Diseases, Vol. 13, No. 1, 01.2007, p. 18-24.

Research output: Contribution to journalArticle

Rahman, M, Sultana, R, Ahmed, G, Nahar, S, Hassan, ZM, Saiada, F, Podder, G, Faruque, ASG, Siddique, AK, Sack, DA, Matthijnssens, J, Van Ranst, M & Azim, T 2007, 'Prevalence of G2P[4] and G12P[6] rotavirus, Bangladesh', Emerging Infectious Diseases, vol. 13, no. 1, pp. 18-24.
Rahman M, Sultana R, Ahmed G, Nahar S, Hassan ZM, Saiada F et al. Prevalence of G2P[4] and G12P[6] rotavirus, Bangladesh. Emerging Infectious Diseases. 2007 Jan;13(1):18-24.
Rahman, Mustafizur ; Sultana, Rasheda ; Ahmed, Giasuddin ; Nahar, Sharifun ; Hassan, Zahid M. ; Saiada, Farjana ; Podder, Goutam ; Faruque, Abu S G ; Siddique, A. K. ; Sack, David A. ; Matthijnssens, Jelle ; Van Ranst, Marc ; Azim, Tasnim. / Prevalence of G2P[4] and G12P[6] rotavirus, Bangladesh. In: Emerging Infectious Diseases. 2007 ; Vol. 13, No. 1. pp. 18-24.
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