TY - JOUR
T1 - Prevalence of G2P[4] and G12P[6] rotavirus, Bangladesh
AU - Rahman, Mustafizur
AU - Sultana, Rasheda
AU - Ahmed, Giasuddin
AU - Nahar, Sharifun
AU - Hassan, Zahid M.
AU - Saiada, Farjana
AU - Podder, Goutam
AU - Faruque, Abu S.G.
AU - Siddique, A. K.
AU - Sack, David A.
AU - Matthijnssens, Jelle
AU - Van Ranst, Marc
AU - Azim, Tasnim
PY - 2007/1
Y1 - 2007/1
N2 - Approximately 20,000 stool specimens from patients with diarrhea visiting 1 urban and 1 rural hospital in Bangladesh during January 2001-May 2006 were tested for group A rotavirus antigen, and 4,712 (24.0%) were positive. G and P genotyping was performed on a subset of 10% of the positive samples (n = 471). During the 2001-2005 rotavirus seasons, G1P[8] (36.4%) and G9P[8] (27.7%) were the dominant strains, but G2[4] and G12P[6] were present in 15.4% and 3.1% of the rotavirus-positive patients, respectively. During the 2005-06 rotavirus season, G2P[4] (43.2%) appeared as the most prevalent strain, and G12P[6] became a more prevalent strain (11.1%) during this season. Because recently licensed rotavirus vaccines include only the P[8] specificity, it is unknown how the vaccines will perform in settings where non-P[8] types are prevalent.
AB - Approximately 20,000 stool specimens from patients with diarrhea visiting 1 urban and 1 rural hospital in Bangladesh during January 2001-May 2006 were tested for group A rotavirus antigen, and 4,712 (24.0%) were positive. G and P genotyping was performed on a subset of 10% of the positive samples (n = 471). During the 2001-2005 rotavirus seasons, G1P[8] (36.4%) and G9P[8] (27.7%) were the dominant strains, but G2[4] and G12P[6] were present in 15.4% and 3.1% of the rotavirus-positive patients, respectively. During the 2005-06 rotavirus season, G2P[4] (43.2%) appeared as the most prevalent strain, and G12P[6] became a more prevalent strain (11.1%) during this season. Because recently licensed rotavirus vaccines include only the P[8] specificity, it is unknown how the vaccines will perform in settings where non-P[8] types are prevalent.
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U2 - 10.3201/eid1301.060910
DO - 10.3201/eid1301.060910
M3 - Article
C2 - 17370511
AN - SCOPUS:33846107466
SN - 1080-6040
VL - 13
SP - 18
EP - 24
JO - Emerging infectious diseases
JF - Emerging infectious diseases
IS - 1
ER -