Prevalence of atrial arrhythmias in arrhythmogenic right ventricular dysplasia/cardiomyopathy

Christian F. Camm, Cynthia Anne James, Crystal Tichnell, Brittney Murray, Aditya Bhonsale, Anneline S J M Te Riele, Daniel P. Judge, Harikrishna Tandri, Hugh Calkins

Research output: Contribution to journalArticle

Abstract

Background Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is an inherited cardiomyopathy, characterized by right ventricular dysfunction and ventricular arrhythmias. Limited information is available concerning atrial arrhythmias in ARVD/C. Objective The purpose of this study was to characterize spontaneous atrial arrhythmias in a large registry population of ARVD/C patients. Methods Patients (n = 248) from the Johns Hopkins ARVD/C registry who met the diagnostic criteria and had undertaken genotype analysis were included. Medical records of each were reviewed to ascertain incidence and characteristics of atrial arrhythmia episodes. Detailed demographic, phenotypic, and structural information was obtained from registry data. Results Thirty-five patients with ARVD/C (14%) experienced one or more types of atrial arrhythmia during median follow-up of 5.78 (interquartile range 8.52) years. Atrial fibrillation was the most common atrial arrhythmia, occurring in 80% of ARVD/C patients with atrial arrhythmias. Patients developed atrial arrhythmias at a mean age of 43.0 ± 14.0 years. Atrial arrhythmia patients obtained a total of 22 inappropriate implantable cardioverter-defibrillator shocks during follow-up. Older age at last follow-up (P

Original languageEnglish (US)
Pages (from-to)1661-1668
Number of pages8
JournalHeart Rhythm
Volume10
Issue number11
DOIs
StatePublished - Nov 2013

Fingerprint

Arrhythmogenic Right Ventricular Dysplasia
Cardiac Arrhythmias
Registries
Right Ventricular Dysfunction
Implantable Defibrillators
Cardiomyopathies
Atrial Fibrillation
Medical Records
Shock
Genotype
Demography

Keywords

  • Arrhythmogenic right ventricular cardiomyopathy
  • Arrhythmogenic right ventricular dysplasia
  • Atrial arrhythmia
  • Atrial fibrillation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

Cite this

Prevalence of atrial arrhythmias in arrhythmogenic right ventricular dysplasia/cardiomyopathy. / Camm, Christian F.; James, Cynthia Anne; Tichnell, Crystal; Murray, Brittney; Bhonsale, Aditya; Te Riele, Anneline S J M; Judge, Daniel P.; Tandri, Harikrishna; Calkins, Hugh.

In: Heart Rhythm, Vol. 10, No. 11, 11.2013, p. 1661-1668.

Research output: Contribution to journalArticle

Camm, Christian F. ; James, Cynthia Anne ; Tichnell, Crystal ; Murray, Brittney ; Bhonsale, Aditya ; Te Riele, Anneline S J M ; Judge, Daniel P. ; Tandri, Harikrishna ; Calkins, Hugh. / Prevalence of atrial arrhythmias in arrhythmogenic right ventricular dysplasia/cardiomyopathy. In: Heart Rhythm. 2013 ; Vol. 10, No. 11. pp. 1661-1668.
@article{a89d7de373b244c6a08abafb4a9cd69c,
title = "Prevalence of atrial arrhythmias in arrhythmogenic right ventricular dysplasia/cardiomyopathy",
abstract = "Background Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is an inherited cardiomyopathy, characterized by right ventricular dysfunction and ventricular arrhythmias. Limited information is available concerning atrial arrhythmias in ARVD/C. Objective The purpose of this study was to characterize spontaneous atrial arrhythmias in a large registry population of ARVD/C patients. Methods Patients (n = 248) from the Johns Hopkins ARVD/C registry who met the diagnostic criteria and had undertaken genotype analysis were included. Medical records of each were reviewed to ascertain incidence and characteristics of atrial arrhythmia episodes. Detailed demographic, phenotypic, and structural information was obtained from registry data. Results Thirty-five patients with ARVD/C (14{\%}) experienced one or more types of atrial arrhythmia during median follow-up of 5.78 (interquartile range 8.52) years. Atrial fibrillation was the most common atrial arrhythmia, occurring in 80{\%} of ARVD/C patients with atrial arrhythmias. Patients developed atrial arrhythmias at a mean age of 43.0 ± 14.0 years. Atrial arrhythmia patients obtained a total of 22 inappropriate implantable cardioverter-defibrillator shocks during follow-up. Older age at last follow-up (P",
keywords = "Arrhythmogenic right ventricular cardiomyopathy, Arrhythmogenic right ventricular dysplasia, Atrial arrhythmia, Atrial fibrillation",
author = "Camm, {Christian F.} and James, {Cynthia Anne} and Crystal Tichnell and Brittney Murray and Aditya Bhonsale and {Te Riele}, {Anneline S J M} and Judge, {Daniel P.} and Harikrishna Tandri and Hugh Calkins",
year = "2013",
month = "11",
doi = "10.1016/j.hrthm.2013.08.032",
language = "English (US)",
volume = "10",
pages = "1661--1668",
journal = "Heart Rhythm",
issn = "1547-5271",
publisher = "Elsevier",
number = "11",

}

TY - JOUR

T1 - Prevalence of atrial arrhythmias in arrhythmogenic right ventricular dysplasia/cardiomyopathy

AU - Camm, Christian F.

AU - James, Cynthia Anne

AU - Tichnell, Crystal

AU - Murray, Brittney

AU - Bhonsale, Aditya

AU - Te Riele, Anneline S J M

AU - Judge, Daniel P.

AU - Tandri, Harikrishna

AU - Calkins, Hugh

PY - 2013/11

Y1 - 2013/11

N2 - Background Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is an inherited cardiomyopathy, characterized by right ventricular dysfunction and ventricular arrhythmias. Limited information is available concerning atrial arrhythmias in ARVD/C. Objective The purpose of this study was to characterize spontaneous atrial arrhythmias in a large registry population of ARVD/C patients. Methods Patients (n = 248) from the Johns Hopkins ARVD/C registry who met the diagnostic criteria and had undertaken genotype analysis were included. Medical records of each were reviewed to ascertain incidence and characteristics of atrial arrhythmia episodes. Detailed demographic, phenotypic, and structural information was obtained from registry data. Results Thirty-five patients with ARVD/C (14%) experienced one or more types of atrial arrhythmia during median follow-up of 5.78 (interquartile range 8.52) years. Atrial fibrillation was the most common atrial arrhythmia, occurring in 80% of ARVD/C patients with atrial arrhythmias. Patients developed atrial arrhythmias at a mean age of 43.0 ± 14.0 years. Atrial arrhythmia patients obtained a total of 22 inappropriate implantable cardioverter-defibrillator shocks during follow-up. Older age at last follow-up (P

AB - Background Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is an inherited cardiomyopathy, characterized by right ventricular dysfunction and ventricular arrhythmias. Limited information is available concerning atrial arrhythmias in ARVD/C. Objective The purpose of this study was to characterize spontaneous atrial arrhythmias in a large registry population of ARVD/C patients. Methods Patients (n = 248) from the Johns Hopkins ARVD/C registry who met the diagnostic criteria and had undertaken genotype analysis were included. Medical records of each were reviewed to ascertain incidence and characteristics of atrial arrhythmia episodes. Detailed demographic, phenotypic, and structural information was obtained from registry data. Results Thirty-five patients with ARVD/C (14%) experienced one or more types of atrial arrhythmia during median follow-up of 5.78 (interquartile range 8.52) years. Atrial fibrillation was the most common atrial arrhythmia, occurring in 80% of ARVD/C patients with atrial arrhythmias. Patients developed atrial arrhythmias at a mean age of 43.0 ± 14.0 years. Atrial arrhythmia patients obtained a total of 22 inappropriate implantable cardioverter-defibrillator shocks during follow-up. Older age at last follow-up (P

KW - Arrhythmogenic right ventricular cardiomyopathy

KW - Arrhythmogenic right ventricular dysplasia

KW - Atrial arrhythmia

KW - Atrial fibrillation

UR - http://www.scopus.com/inward/record.url?scp=84887004689&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84887004689&partnerID=8YFLogxK

U2 - 10.1016/j.hrthm.2013.08.032

DO - 10.1016/j.hrthm.2013.08.032

M3 - Article

VL - 10

SP - 1661

EP - 1668

JO - Heart Rhythm

JF - Heart Rhythm

SN - 1547-5271

IS - 11

ER -