Preservation of voluntary saccades after intracarotid injection of barbiturate

R. P. Lesser, R. J. Leigh, D. S. Dinner, H. Lüders, H. H. Morris, R. L. Tomsak, K. I. Lockwood

Research output: Contribution to journalArticle

Abstract

We studied voluntary saccades in 44 patients undergoing Wada testing before surgery for intractable epilepsy. After intracarotid injection of barbiturate, and while they were hemiplegic, patients could still make voluntary saccades toward or away from the side of injection. Sustained ipsiversive deviation of gaze was not noted. Saccades made away from the side of injection were slower than ipsilateral saccades in only 3 of 10 tests. These data support the hypothesis of parallel, independent pathways from the frontal eye fields and from the superior colliculi to the brainstem reticular nuclei that generate saccades.

Original languageEnglish (US)
Pages (from-to)1108-1112
Number of pages5
JournalNeurology
Volume35
Issue number8
DOIs
StatePublished - Aug 1985

ASJC Scopus subject areas

  • Clinical Neurology

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    Lesser, R. P., Leigh, R. J., Dinner, D. S., Lüders, H., Morris, H. H., Tomsak, R. L., & Lockwood, K. I. (1985). Preservation of voluntary saccades after intracarotid injection of barbiturate. Neurology, 35(8), 1108-1112. https://doi.org/10.1212/wnl.35.8.1108