TY - JOUR
T1 - Present understanding of the relationship between exercise and arrhythmogenic right ventricular dysplasia/cardiomyopathy
AU - Rojas, Anne
AU - Calkins, Hugh
N1 - Funding Information:
Sources of funding: The authors wish to acknowledge funding from the Dr. Francis P. Chiaramonte Private Foundation, St. Jude Medical Inc., and Medtronic Inc. The Johns Hopkins ARVD/C Program is supported by the Leyla Erkan Family Fund for ARVD Research, the Dr. Satish, Rupal, and Robin Shah ARVD Fund at Johns Hopkins, the Bogle Foundation, the Healing Hearts Foundation, the Campanella family, the Patrick J. Harrison Family, the Peter French Memorial Foundation, and the Wilmerding Endowments.
Funding Information:
Disclosures: Dr. Calkins receives research support from the Dr. Francis P. Chiaramonte Private Foundation, St. Jude Medical Inc., and Medtronic Inc. The other authors report no conflict of interest.
Publisher Copyright:
© 2015 Elsevier Inc.
PY - 2015/4/1
Y1 - 2015/4/1
N2 - Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is an inherited cardiomyopathy that is characterized clinically by ventricular arrhythmias and an increased risk of sudden death and pathologically by fibrofatty replacement of the myocardium. Soon after the initial description of the disease, investigators and clinicians caring for patients with ARVD/C recognized a link between exercise and ARVD/C. In this article, we review the considerable body of epidemiologic data, basic research, and clinical research supporting the link between exercise and the development and outcomes of ARVD/C. Based on these data, we now advise that patients with ARVD/C avoid participation in competitive athletics and limit exercise as much as possible.
AB - Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is an inherited cardiomyopathy that is characterized clinically by ventricular arrhythmias and an increased risk of sudden death and pathologically by fibrofatty replacement of the myocardium. Soon after the initial description of the disease, investigators and clinicians caring for patients with ARVD/C recognized a link between exercise and ARVD/C. In this article, we review the considerable body of epidemiologic data, basic research, and clinical research supporting the link between exercise and the development and outcomes of ARVD/C. Based on these data, we now advise that patients with ARVD/C avoid participation in competitive athletics and limit exercise as much as possible.
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U2 - 10.1016/j.tcm.2014.10.007
DO - 10.1016/j.tcm.2014.10.007
M3 - Review article
C2 - 25666490
AN - SCOPUS:84925243572
SN - 1050-1738
VL - 25
SP - 181
EP - 188
JO - Trends in Cardiovascular Medicine
JF - Trends in Cardiovascular Medicine
IS - 3
ER -