Presence of Posterior Staphyloma in Congenital Cataract Children

Xiangjia Zhu, Wenwen He, Yu Du, Courtney L. Kraus, Qingguo Xu, Ting Sun, Jia Yu, Yi Lu

Research output: Contribution to journalArticlepeer-review


Purpose: To investigate the prevalence of posterior staphyloma (PS) in congenital cataract children and its role in predicting postoperative axial elongation. Materials and Methods: Preoperative prevalence of PS in 520 congenital cataract patients was reviewed and compared with that of the healthy eyes of 300 unilateral traumatic cataract children after 1:1 propensity score matching. Then, 32 pseudophakic children with preoperative PS and 48 age-matched pseudophakic controls without preoperative PS were followed up after the surgery, to compare their axial growth rates and refractive changes. Results: Congenital cataract was significantly associated with the presence of PS (OR: 14.88, P =.009) after propensity score matching. Even in congenital cataract eyes with axial length <26 mm, 5% were identified with PS on B-scan: ≤22 mm: 3%, 22–24 mm: 5% and 24–26 mm: 13%. Eyes with preoperative PS exhibited faster postoperative axial growth than those without, especially in bilateral cases or in children undergoing surgery before 8 years old (≤4 years: 0.53 ± 0.33 vs 0.30 ± 0.21 mm/y P =.028; 4–8 years: 0.37 ± 0.26 vs 0.23 ± 0.15 mm/y P =.044). Myopic shift after surgery was also more significant in children with preoperative PS than in those without (−1.10 ± 0.50 vs −0.60 ± 0.47D/y, P <.001). Conclusions: Congenital cataract is a risk factor for PS. Preoperative PS in pediatric cataract eyes may be an indicator of excessive postoperative axial elongation, especially in bilateral cases or in cases undergoing cataract surgery at a younger age. Our findings may also promote better clinical decision-making in intraocular lens power selection for pediatric population.

Original languageEnglish (US)
Pages (from-to)1319-1324
Number of pages6
JournalCurrent Eye Research
Issue number12
StatePublished - Dec 2 2019


  • Congenital cataract
  • axial length
  • myopic shift
  • posterior staphyloma

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience


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