Presence of γE in nasal washings and sputum from asthmatic patients

Kimishige Ishizaka, Richard W. Newcomb

Research output: Contribution to journalArticlepeer-review

Abstract

Immunoglobulin E (γE) was detected in nasal washings and sputum obtained from some asthmatic patients. The measurement of γE concentration was not affected by the presence of enzymes or insoluble components of the exocrine fluids. Quantitatively, the γE γG concentration ratios in the specimens were usually higher than those in sera of the same patients. The results suggested the possibility that locally formed γE may be secreted, at least in part, into nasal fluids and sputum.

Original languageEnglish (US)
Pages (from-to)197-204
Number of pages8
JournalJournal of Allergy
Volume46
Issue number4
DOIs
StatePublished - Oct 1970

ASJC Scopus subject areas

  • Medicine(all)

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