Preparation and optimization of new 4-(2-(indolin-1-yl)-2-oxoethyl)-2- morpholinothiazole-5-carboxylic acid and amide derivatives as potent and selective PI3Kβ inhibitors

Victor Certal, Frank Halley, Angela Virone-Oddos, Bruno Filoche-Rommé, Jean Christophe Carry, Florence Gruss-Leleu, Luc Bertin, Houlfa Guizani, Fabienne Pilorge, Patrick Richepin, Andreas Karlsson, Véronique Charrier, Pierre Yves Abecassis, Loic Vincent, Jean Paul Nicolas, Christoph Lengauer, Carlos Garcia-Echeverria, Laurent Schio

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