Prenatal sex determination by observation of the x-chromatin and the y-chromatin of exfoliated amniotic fluid cells

Kap Soon Ju, I. James Park, Howard W. Jones, Kevin J. Winn

Research output: Contribution to journalArticle

Abstract

Using direct smears of amniotic fluid cells fixed by the flame drying technic, the validity of sex determination by X-chromatin and Y-chromatin counts has been examined. In 112 cases, the sex determination by examination of the X-chromatin was correct in 109 (97%) and was correct by the Y-chromatin technic in 111 (99%). It is concluded that prenatal sex determination by examination of the X-chromatin or the Y-chromatin from fresh amniotic fluid cells is a valuable, rapid, practical method of prenatal sex determination.

Original languageEnglish (US)
Pages (from-to)287-290
Number of pages4
JournalObstetrics and gynecology
Volume47
Issue number3
StatePublished - Mar 1976

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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