Prenatal testing for hEmoglobinopathics has been available since 1974, using fetal blood samples, and since 1978, using fetal DNA. Close to 2000 cases were studied by analysis of fetal globin synthesis, and approximately 100 by restriction enzyme techniques. More than 20 centers worldwide are performing these tests. The safety and reliability of these tests are now clear, and they have a major role in the counselling of families where there is a risk of sickle cell disease or thalassemia.
|Original language||English (US)|
|Number of pages||8|
|Journal||Journal of Pediatric Hematology/Oncology|
|State||Published - 1983|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health