Prenatal diagnosis of ductus venosus agenesis

A report of two cases and review of the literature

U. Gembruch, Ahmet Baschat, A. Caliebe, L. Gortner

Research output: Contribution to journalArticle

Abstract

Anomalies of venous return due to absence of the ductus venosus have been described in the literature. This is a report of the prenatal diagnosis of two cases of isolated ductus venosus agenesis occurring at 20 and 37 weeks' gestation, confirmed postnatally by color-coded Doppler sonography. In both cases the hepatic veins assumed the function of the ductus venosus without compromising fetal hemodynamics or causing hydrops. In the first case, a healthy female infant was delivered at term. In the second case, a 46,XY,dup(8) (q21.1q22)[35]/47,idem,+r(8)[15] karyotype was diagnosed by amniocentesis. The male new-born showed facial anomalies, a bell-shaped thorax and increased intermamillary distance. There was muscular hypotonia, delayed psychomotor development and an inspiratory stridor leading to obstructive nocturnal dyspnea. On the basis of our observations in these two cases and previous reports from animal studies, we conclude that absence of the ductus venosus may be compatible with normal fetal development without relevant disturbance of circulation and oxygenation.

Original languageEnglish (US)
Pages (from-to)185-189
Number of pages5
JournalUltrasound in Obstetrics and Gynecology
Volume11
Issue number3
DOIs
StatePublished - 1998
Externally publishedYes

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Doppler Color Ultrasonography
Muscle Hypotonia
Hepatic Veins
Amniocentesis
Respiratory Sounds
Fetal Development
Prenatal Diagnosis
hypotonia
Karyotype
Dyspnea
Edema
dyspnea
Thorax
Hemodynamics
anomalies
thorax
Pregnancy
hemodynamics
oxygenation
veins

Keywords

  • Doppler ultrasound
  • Ductus venosus
  • Ductus venosus agenesis
  • Fetal surveillance
  • Fetus
  • Prenatal diagnosis
  • Ultrasound
  • Venous flow

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Reproductive Medicine
  • Acoustics and Ultrasonics

Cite this

Prenatal diagnosis of ductus venosus agenesis : A report of two cases and review of the literature. / Gembruch, U.; Baschat, Ahmet; Caliebe, A.; Gortner, L.

In: Ultrasound in Obstetrics and Gynecology, Vol. 11, No. 3, 1998, p. 185-189.

Research output: Contribution to journalArticle

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