Prenatal diagnosis of ductus venosus agenesis: A report of two cases and review of the literature

U. Gembruch, A. A. Baschat, A. Caliebe, L. Gortner

Research output: Contribution to journalArticlepeer-review

Abstract

Anomalies of venous return due to absence of the ductus venosus have been described in the literature. This is a report of the prenatal diagnosis of two cases of isolated ductus venosus agenesis occurring at 20 and 37 weeks' gestation, confirmed postnatally by color-coded Doppler sonography. In both cases the hepatic veins assumed the function of the ductus venosus without compromising fetal hemodynamics or causing hydrops. In the first case, a healthy female infant was delivered at term. In the second case, a 46,XY,dup(8) (q21.1q22)[35]/47,idem,+r(8)[15] karyotype was diagnosed by amniocentesis. The male new-born showed facial anomalies, a bell-shaped thorax and increased intermamillary distance. There was muscular hypotonia, delayed psychomotor development and an inspiratory stridor leading to obstructive nocturnal dyspnea. On the basis of our observations in these two cases and previous reports from animal studies, we conclude that absence of the ductus venosus may be compatible with normal fetal development without relevant disturbance of circulation and oxygenation.

Original languageEnglish (US)
Pages (from-to)185-189
Number of pages5
JournalUltrasound in Obstetrics and Gynecology
Volume11
Issue number3
DOIs
StatePublished - 1998
Externally publishedYes

Keywords

  • Doppler ultrasound
  • Ductus venosus
  • Ductus venosus agenesis
  • Fetal surveillance
  • Fetus
  • Prenatal diagnosis
  • Ultrasound
  • Venous flow

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Reproductive Medicine
  • Radiology Nuclear Medicine and imaging
  • Obstetrics and Gynecology

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