Premature ovarian failure associated with autoantibodies to the zona pellucida

Samuel Smith, S. Hosid

Research output: Contribution to journalArticle

Abstract

Immune disturbances are noted in up to 35% of women with premature ovarian failure. Previous investigators have focused on the presence of antibodies directed against steroid secreting cells of the ovary and the presence of lymphocytic infiltration in ovarian biopsy specimens. The authors report two cases of premature ovarian failure associated with antibodies directed against the zona pellucida. One of these two patients conceived while on estrogen replacement therapy.

Original languageEnglish (US)
Pages (from-to)316-319
Number of pages4
JournalInternational Journal of Fertility and Menopausal Studies
Volume39
Issue number6
StatePublished - Jan 1 1994
Externally publishedYes

Fingerprint

Primary Ovarian Insufficiency
Zona Pellucida
Autoantibodies
Estrogen Replacement Therapy
Antibodies
Ovary
Steroids
Research Personnel
Biopsy

Keywords

  • (premature) ovarian failure
  • estrogen replacement therapy
  • immune system
  • zona pellucida antibodies

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Premature ovarian failure associated with autoantibodies to the zona pellucida. / Smith, Samuel; Hosid, S.

In: International Journal of Fertility and Menopausal Studies, Vol. 39, No. 6, 01.01.1994, p. 316-319.

Research output: Contribution to journalArticle

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