Preliminary, Real-world, Multicenter Experience with Omadacycline for Mycobacterium abscessus Infections

Taylor Morrisette; Sara Alosaimy; Julie V. Philley; Carly Wadle; Catessa Howard; Andrew J. Webb; Michael P. Veve; Melissa L. Barger; Jeannette Bouchard; Tristan W. Gore; Abdalhamid M. Lagnf; Iman Ansari; Carlos Mejia-Chew; Keira A. Cohen; Michael J. Rybak

doi:10.1093/ofid/ofab002

Preliminary, Real-world, Multicenter Experience with Omadacycline for Mycobacterium abscessus Infections

Taylor Morrisette, Sara Alosaimy, Julie V. Philley, Carly Wadle, Catessa Howard, Andrew J. Webb, Michael P. Veve, Melissa L. Barger, Jeannette Bouchard, Tristan W. Gore, Abdalhamid M. Lagnf, Iman Ansari, Carlos Mejia-Chew, Keira A. Cohen, Michael J. Rybak

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Twelve patients were treated with omadacycline (OMC) as part of a multidrug regimen for Mycobacterium abscessus. The majority of infections were of pulmonary origin (7/12; 58.3%). The median (interquartile range) duration of OMC was 6.2 (4.2-11.0) months. Clinical success occurred in 9/12 (75.0%) patients. Three patients experienced a possible adverse effect while on therapy.

Original language	English (US)
Article number	ofab002
Journal	Open Forum Infectious Diseases
Volume	8
Issue number	2
DOIs	https://doi.org/10.1093/ofid/ofab002
State	Published - Feb 1 2021

Keywords

Mycobacterium abscessus
omadacycline
rapidly growing nontuberculous mycobacteria

ASJC Scopus subject areas

Infectious Diseases
Oncology

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10.1093/ofid/ofab002

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Morrisette, T., Alosaimy, S., Philley, J. V., Wadle, C., Howard, C., Webb, A. J., Veve, M. P., Barger, M. L., Bouchard, J., Gore, T. W., Lagnf, A. M., Ansari, I., Mejia-Chew, C., Cohen, K. A., & Rybak, M. J. (2021). Preliminary, Real-world, Multicenter Experience with Omadacycline for Mycobacterium abscessus Infections. Open Forum Infectious Diseases, 8(2), Article ofab002. https://doi.org/10.1093/ofid/ofab002

Morrisette, T, Alosaimy, S, Philley, JV, Wadle, C, Howard, C, Webb, AJ, Veve, MP, Barger, ML, Bouchard, J, Gore, TW, Lagnf, AM, Ansari, I, Mejia-Chew, C, Cohen, KA & Rybak, MJ 2021, 'Preliminary, Real-world, Multicenter Experience with Omadacycline for Mycobacterium abscessus Infections', Open Forum Infectious Diseases, vol. 8, no. 2, ofab002. https://doi.org/10.1093/ofid/ofab002

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AU - Howard, Catessa

AU - Webb, Andrew J.

AU - Veve, Michael P.

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AU - Gore, Tristan W.

AU - Lagnf, Abdalhamid M.

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Preliminary, Real-world, Multicenter Experience with Omadacycline for Mycobacterium abscessus Infections

Abstract

Keywords

ASJC Scopus subject areas

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