Prehypertension Is Associated With Abnormalities of Cardiac Structure and Function in the Atherosclerosis Risk in Communities Study

Angela B S Santos, Deepak K. Gupta, Natalie A. Bello, Mauro Gori, Brian Claggett, Flavio D. Fuchs, Amil M. Shah, Josef Coresh, A. Richey Sharrett, Susan Cheng, Scott D. Solomon

Research output: Contribution to journalArticle

Abstract

BACKGROUND: Prehypertension (blood pressure (BP) of 120-139mm Hg systolic and/or 80-89mm Hg diastolic) is highly prevalent and is associated with increased cardiovascular risk. Our goal was to investigate the extent to which prehypertension is associated with end-organ alterations in cardiac structure and function in a large biracial cohort of older men and women. METHODS: We studied 4,871 participants of the Atherosclerosis Risk in Communities (ARIC) study who attended visit 5 (2011-2013) and underwent two-dimensional echocardiography while free of prevalent coronary heart disease or heart failure. We categorized participants into 3 groups: optimal BP (BP

Original languageEnglish (US)
Pages (from-to)568-574
Number of pages7
JournalAmerican Journal of Hypertension
Volume29
Issue number5
DOIs
StatePublished - May 1 2016

Keywords

  • blood pressure
  • cardiovascular pathophysiology
  • echocardiography
  • prehypertension

ASJC Scopus subject areas

  • Internal Medicine

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    Santos, A. B. S., Gupta, D. K., Bello, N. A., Gori, M., Claggett, B., Fuchs, F. D., Shah, A. M., Coresh, J., Sharrett, A. R., Cheng, S., & Solomon, S. D. (2016). Prehypertension Is Associated With Abnormalities of Cardiac Structure and Function in the Atherosclerosis Risk in Communities Study. American Journal of Hypertension, 29(5), 568-574. https://doi.org/10.1093/ajh/hpv156