Pregnancy, postpartum autoimmune thyroiditis, and autoimmune hypophysitis: Intimate relationships

Melissa A. Landek-Salgado, Angelika Gutenberg, Isabella Lupi, Hiroaki Kimura, Stefano Mariotti, Noel R. Rose, Patrizio Caturegli

Research output: Contribution to journalReview articlepeer-review

Abstract

Autoimmune diseases comprise a group of about 85 heterogeneous conditions that can affect virtually any organ and tissue in the body. Many autoimmune diseases change significantly during pregnancy: some ameliorate, some worsen, and others are unaffected. Two autoimmune diseases present prominently in relation to pregnancy: postpartum autoimmune thyroiditis and autoimmune hypophysitis. This article will review the current state of knowledge of the immunological changes that occur during normal pregnancy, and will explore the striking temporal association with pregnancy observed in thyroiditis and hypophysitis.

Original languageEnglish (US)
Pages (from-to)153-157
Number of pages5
JournalAutoimmunity Reviews
Volume9
Issue number3
DOIs
StatePublished - Jan 2010

Keywords

  • Hypophysitis
  • Postpartum thyroiditis
  • Pregnancy

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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