Pregnancy outcome in 98 women exposed to diethylstilbestrol in utero, their mothers, and unexposed siblings

C. E. Mangan, L. Borow, M. M. Burtnett-Rubin, V. Egan, R. L. Giuntoli, J. J. Mikuta

Research output: Contribution to journalArticle

Abstract

The reproductive capability and labor complications of 98 women exposed to diethylstilbestrol (DES) in utero were compared with those of 3 separate control groups. The controls consisted of 167 age-matched, normal women, 20 siblings not exposed to DES who had achieved pregnancy, and their mothers. Spontaneous abortion, ectopic pregnancy, incompetent cervix, and premature labor occurred significantly more often in the DES-exposed population than in the normal controls. The controls also achieved a higher percentage of desired pregnancies overall; this was statistically significant (89.6 versus 75.0%, P

Original languageEnglish (US)
Pages (from-to)315-319
Number of pages5
JournalObstetrics and Gynecology
Volume59
Issue number3
Publication statusPublished - 1982
Externally publishedYes

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ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Mangan, C. E., Borow, L., Burtnett-Rubin, M. M., Egan, V., Giuntoli, R. L., & Mikuta, J. J. (1982). Pregnancy outcome in 98 women exposed to diethylstilbestrol in utero, their mothers, and unexposed siblings. Obstetrics and Gynecology, 59(3), 315-319.