Preferential alignment of birefringent tissue measured with polarization sensitive techniques

J. C. Ramella-Roman; T. Ruiz; P. Ghassemi; T. E. Travis; J. W. Shupp; J. Chue-Sang; Y. Bai

doi:10.1117/12.2081338

Preferential alignment of birefringent tissue measured with polarization sensitive techniques

J. C. Ramella-Roman, T. Ruiz, P. Ghassemi, T. E. Travis, J. W. Shupp, J. Chue-Sang, Y. Bai

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Scopus citations

Abstract

Assessing collagen alignment is of interest when evaluating a therapeutic strategy and evaluating its outcome in scar management. In this work we introduce a theoretical and experimental methodology for the quantification of collagen and birefringent media alignment based on polarized light transport. The technique relies on the fact that these materials exhibit directional anisotropy. A polarized Monte Carlo model and a spectro-polarimetric imaging system were devised to predict and measure the impact of birefringence on an impinging polarized light beam. Experiments conducted on birefringent phantoms, and biological samples consisting of highly packed parallel birefringent fibers, showed a good agreement with the analytical results.

Original language	English (US)
Title of host publication	Photonic Therapeutics and Diagnostics XI
Publisher	SPIE
Volume	9303
ISBN (Print)	9781628413939
DOIs	https://doi.org/10.1117/12.2081338
State	Published - 2015
Externally published	Yes
Event	Photonic Therapeutics and Diagnostics XI - San Francisco, United States Duration: Feb 7 2015 → Feb 8 2015

Other

Other	Photonic Therapeutics and Diagnostics XI
Country/Territory	United States
City	San Francisco
Period	2/7/15 → 2/8/15

Keywords

Collagen
Directional Anisotropy
Polarimetry

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics
Electronic, Optical and Magnetic Materials
Biomaterials
Radiology Nuclear Medicine and imaging

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10.1117/12.2081338

Cite this

Ramella-Roman, JC, Ruiz, T, Ghassemi, P, Travis, TE, Shupp, JW, Chue-Sang, J & Bai, Y 2015, Preferential alignment of birefringent tissue measured with polarization sensitive techniques. in Photonic Therapeutics and Diagnostics XI. vol. 9303, 93030I, SPIE, Photonic Therapeutics and Diagnostics XI, San Francisco, United States, 2/7/15. https://doi.org/10.1117/12.2081338

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title = "Preferential alignment of birefringent tissue measured with polarization sensitive techniques",

abstract = "Assessing collagen alignment is of interest when evaluating a therapeutic strategy and evaluating its outcome in scar management. In this work we introduce a theoretical and experimental methodology for the quantification of collagen and birefringent media alignment based on polarized light transport. The technique relies on the fact that these materials exhibit directional anisotropy. A polarized Monte Carlo model and a spectro-polarimetric imaging system were devised to predict and measure the impact of birefringence on an impinging polarized light beam. Experiments conducted on birefringent phantoms, and biological samples consisting of highly packed parallel birefringent fibers, showed a good agreement with the analytical results.",

keywords = "Collagen, Directional Anisotropy, Polarimetry",

author = "Ramella-Roman, {J. C.} and T. Ruiz and P. Ghassemi and Travis, {T. E.} and Shupp, {J. W.} and J. Chue-Sang and Y. Bai",

year = "2015",

doi = "10.1117/12.2081338",

language = "English (US)",

isbn = "9781628413939",

volume = "9303",

booktitle = "Photonic Therapeutics and Diagnostics XI",

publisher = "SPIE",

note = "Photonic Therapeutics and Diagnostics XI ; Conference date: 07-02-2015 Through 08-02-2015",

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TY - GEN

T1 - Preferential alignment of birefringent tissue measured with polarization sensitive techniques

AU - Ramella-Roman, J. C.

AU - Ruiz, T.

AU - Ghassemi, P.

AU - Travis, T. E.

AU - Shupp, J. W.

AU - Chue-Sang, J.

AU - Bai, Y.

PY - 2015

Y1 - 2015

N2 - Assessing collagen alignment is of interest when evaluating a therapeutic strategy and evaluating its outcome in scar management. In this work we introduce a theoretical and experimental methodology for the quantification of collagen and birefringent media alignment based on polarized light transport. The technique relies on the fact that these materials exhibit directional anisotropy. A polarized Monte Carlo model and a spectro-polarimetric imaging system were devised to predict and measure the impact of birefringence on an impinging polarized light beam. Experiments conducted on birefringent phantoms, and biological samples consisting of highly packed parallel birefringent fibers, showed a good agreement with the analytical results.

AB - Assessing collagen alignment is of interest when evaluating a therapeutic strategy and evaluating its outcome in scar management. In this work we introduce a theoretical and experimental methodology for the quantification of collagen and birefringent media alignment based on polarized light transport. The technique relies on the fact that these materials exhibit directional anisotropy. A polarized Monte Carlo model and a spectro-polarimetric imaging system were devised to predict and measure the impact of birefringence on an impinging polarized light beam. Experiments conducted on birefringent phantoms, and biological samples consisting of highly packed parallel birefringent fibers, showed a good agreement with the analytical results.

KW - Collagen

KW - Directional Anisotropy

KW - Polarimetry

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U2 - 10.1117/12.2081338

DO - 10.1117/12.2081338

M3 - Conference contribution

AN - SCOPUS:84926637838

SN - 9781628413939

VL - 9303

BT - Photonic Therapeutics and Diagnostics XI

PB - SPIE

T2 - Photonic Therapeutics and Diagnostics XI

Y2 - 7 February 2015 through 8 February 2015

ER -

Preferential alignment of birefringent tissue measured with polarization sensitive techniques

Abstract

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Keywords

ASJC Scopus subject areas

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