Predictors of reported influenza vaccination in HIV-infected women in the United States, 2006-2007 and 2007-2008 seasons

Keri N. Althoff; Kathryn Anastos; Kenrad Edwin Nelson; David D. Celentano; Gerald B. Sharp; Ruth M. Greenblatt; Audrey L. French; Don J. Diamond; Susan Holman; Mary Young; Stephen J. Gange

doi:10.1016/j.ypmed.2010.03.007

Predictors of reported influenza vaccination in HIV-infected women in the United States, 2006-2007 and 2007-2008 seasons

Keri N. Althoff, Kathryn Anastos, Kenrad Edwin Nelson, David D. Celentano, Gerald B. Sharp, Ruth M. Greenblatt, Audrey L. French, Don J. Diamond, Susan Holman, Mary Young, Stephen J. Gange

Bloomberg School of Public Health

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Objective: To estimate the cumulative incidence of self-reported influenza vaccination ("vaccination coverage") and investigate predictors in HIV-infected women. Methods: In an ongoing cohort study of HIV-infected women in five US cities, data from two influenza seasons (2006-2007 n= 1209 and 2007-2008 n= 1161) were used to estimate crude and adjusted prevalence ratios (aPR) and 95% confidence intervals ([,]) from Poisson regression with robust variance models using generalized estimating equations (GEE). Results: In our study, 55% and 57% of HIV-infected women reported vaccination during the 2006-2007 and 2007-2008 seasons, respectively. Using data from both seasons, older age, non-smoking status, CD4 T-lymphocyte (CD4) count ≥200 cells/mm³, and reporting at least one recent healthcare visit was associated with increased vaccination coverage. In the 2007-2008 season, a belief in the protection of the vaccine (aPR=1.38 [1.18, 1.61]) and influenza vaccination in the previous season (aPR=1.66 [1.44, 1.91]) most strongly predicted vaccination status. Conclusion: Interventions to reach unvaccinated HIV-infected women should focus on changing beliefs about the effectiveness of influenza vaccination and target younger women, current smokers, those without recent healthcare visits, or a CD4 count <200 cells/mm³.

Original language	English (US)
Pages (from-to)	223-229
Number of pages	7
Journal	Preventive Medicine
Volume	50
Issue number	5-6
DOIs	https://doi.org/10.1016/j.ypmed.2010.03.007
State	Published - May 2010

Keywords

Adult
Cohort study
Female
HIV/AIDS
Highly active antiretroviral therapy
Influenza vaccine
Multi-center study
United States
Vaccine coverage

ASJC Scopus subject areas

Epidemiology
Public Health, Environmental and Occupational Health

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10.1016/j.ypmed.2010.03.007

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Althoff, K. N., Anastos, K., Nelson, K. E., Celentano, D. D., Sharp, G. B., Greenblatt, R. M., French, A. L., Diamond, D. J., Holman, S., Young, M., & Gange, S. J. (2010). Predictors of reported influenza vaccination in HIV-infected women in the United States, 2006-2007 and 2007-2008 seasons. Preventive Medicine, 50(5-6), 223-229. https://doi.org/10.1016/j.ypmed.2010.03.007

@article{c6c7f04d102e472abd66f44d9be04ccd,

title = "Predictors of reported influenza vaccination in HIV-infected women in the United States, 2006-2007 and 2007-2008 seasons",

abstract = "Objective: To estimate the cumulative incidence of self-reported influenza vaccination ({"}vaccination coverage{"}) and investigate predictors in HIV-infected women. Methods: In an ongoing cohort study of HIV-infected women in five US cities, data from two influenza seasons (2006-2007 n= 1209 and 2007-2008 n= 1161) were used to estimate crude and adjusted prevalence ratios (aPR) and 95% confidence intervals ([,]) from Poisson regression with robust variance models using generalized estimating equations (GEE). Results: In our study, 55% and 57% of HIV-infected women reported vaccination during the 2006-2007 and 2007-2008 seasons, respectively. Using data from both seasons, older age, non-smoking status, CD4 T-lymphocyte (CD4) count ≥200 cells/mm3, and reporting at least one recent healthcare visit was associated with increased vaccination coverage. In the 2007-2008 season, a belief in the protection of the vaccine (aPR=1.38 [1.18, 1.61]) and influenza vaccination in the previous season (aPR=1.66 [1.44, 1.91]) most strongly predicted vaccination status. Conclusion: Interventions to reach unvaccinated HIV-infected women should focus on changing beliefs about the effectiveness of influenza vaccination and target younger women, current smokers, those without recent healthcare visits, or a CD4 count <200 cells/mm3.",

keywords = "Adult, Cohort study, Female, HIV/AIDS, Highly active antiretroviral therapy, Influenza vaccine, Multi-center study, United States, Vaccine coverage",

author = "Althoff, {Keri N.} and Kathryn Anastos and Nelson, {Kenrad Edwin} and Celentano, {David D.} and Sharp, {Gerald B.} and Greenblatt, {Ruth M.} and French, {Audrey L.} and Diamond, {Don J.} and Susan Holman and Mary Young and Gange, {Stephen J.}",

note = "Funding Information: The WIHS is funded by the National Institute of Allergy and Infectious Diseases [grant numbers UO1-AI-35004 , UO1-AI-31834 , UO1-AI-34994 , UO1-AI-34989 , UO1-AI-34993 , and UO1-AI-42590 ]; the National Institute of Child Health and Human Development [grant number UO1-HD-32632 ]. The study is co-funded by the National Cancer Institute; the National Institute on Drug Abuse; and the National Institute on Deafness and Other Communication Disorders. Funding is also provided by the National Center for Research Resources [UCSF-CTSI grant number UL1 RR024131 ]. The contents of this publication are solely the responsibility of the authors and do not necessarily represent the official views of the National Institutes of Health. This work was also supported by the Johns Hopkins Training Program in Sexually Transmitted Infections [ T32-AI050056 ] to [KNA]. ",

year = "2010",

month = may,

doi = "10.1016/j.ypmed.2010.03.007",

language = "English (US)",

volume = "50",

pages = "223--229",

journal = "Preventive Medicine",

issn = "0091-7435",

publisher = "Academic Press Inc.",

number = "5-6",

}

TY - JOUR

T1 - Predictors of reported influenza vaccination in HIV-infected women in the United States, 2006-2007 and 2007-2008 seasons

AU - Althoff, Keri N.

AU - Anastos, Kathryn

AU - Nelson, Kenrad Edwin

AU - Celentano, David D.

AU - Sharp, Gerald B.

AU - Greenblatt, Ruth M.

AU - French, Audrey L.

AU - Diamond, Don J.

AU - Holman, Susan

AU - Young, Mary

AU - Gange, Stephen J.

N1 - Funding Information: The WIHS is funded by the National Institute of Allergy and Infectious Diseases [grant numbers UO1-AI-35004 , UO1-AI-31834 , UO1-AI-34994 , UO1-AI-34989 , UO1-AI-34993 , and UO1-AI-42590 ]; the National Institute of Child Health and Human Development [grant number UO1-HD-32632 ]. The study is co-funded by the National Cancer Institute; the National Institute on Drug Abuse; and the National Institute on Deafness and Other Communication Disorders. Funding is also provided by the National Center for Research Resources [UCSF-CTSI grant number UL1 RR024131 ]. The contents of this publication are solely the responsibility of the authors and do not necessarily represent the official views of the National Institutes of Health. This work was also supported by the Johns Hopkins Training Program in Sexually Transmitted Infections [ T32-AI050056 ] to [KNA].

PY - 2010/5

Y1 - 2010/5

N2 - Objective: To estimate the cumulative incidence of self-reported influenza vaccination ("vaccination coverage") and investigate predictors in HIV-infected women. Methods: In an ongoing cohort study of HIV-infected women in five US cities, data from two influenza seasons (2006-2007 n= 1209 and 2007-2008 n= 1161) were used to estimate crude and adjusted prevalence ratios (aPR) and 95% confidence intervals ([,]) from Poisson regression with robust variance models using generalized estimating equations (GEE). Results: In our study, 55% and 57% of HIV-infected women reported vaccination during the 2006-2007 and 2007-2008 seasons, respectively. Using data from both seasons, older age, non-smoking status, CD4 T-lymphocyte (CD4) count ≥200 cells/mm3, and reporting at least one recent healthcare visit was associated with increased vaccination coverage. In the 2007-2008 season, a belief in the protection of the vaccine (aPR=1.38 [1.18, 1.61]) and influenza vaccination in the previous season (aPR=1.66 [1.44, 1.91]) most strongly predicted vaccination status. Conclusion: Interventions to reach unvaccinated HIV-infected women should focus on changing beliefs about the effectiveness of influenza vaccination and target younger women, current smokers, those without recent healthcare visits, or a CD4 count <200 cells/mm3.

AB - Objective: To estimate the cumulative incidence of self-reported influenza vaccination ("vaccination coverage") and investigate predictors in HIV-infected women. Methods: In an ongoing cohort study of HIV-infected women in five US cities, data from two influenza seasons (2006-2007 n= 1209 and 2007-2008 n= 1161) were used to estimate crude and adjusted prevalence ratios (aPR) and 95% confidence intervals ([,]) from Poisson regression with robust variance models using generalized estimating equations (GEE). Results: In our study, 55% and 57% of HIV-infected women reported vaccination during the 2006-2007 and 2007-2008 seasons, respectively. Using data from both seasons, older age, non-smoking status, CD4 T-lymphocyte (CD4) count ≥200 cells/mm3, and reporting at least one recent healthcare visit was associated with increased vaccination coverage. In the 2007-2008 season, a belief in the protection of the vaccine (aPR=1.38 [1.18, 1.61]) and influenza vaccination in the previous season (aPR=1.66 [1.44, 1.91]) most strongly predicted vaccination status. Conclusion: Interventions to reach unvaccinated HIV-infected women should focus on changing beliefs about the effectiveness of influenza vaccination and target younger women, current smokers, those without recent healthcare visits, or a CD4 count <200 cells/mm3.

KW - Adult

KW - Cohort study

KW - Female

KW - HIV/AIDS

KW - Highly active antiretroviral therapy

KW - Influenza vaccine

KW - Multi-center study

KW - United States

KW - Vaccine coverage

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DO - 10.1016/j.ypmed.2010.03.007

M3 - Article

C2 - 20303362

AN - SCOPUS:77952555271

SN - 0091-7435

VL - 50

SP - 223

EP - 229

JO - Preventive Medicine

JF - Preventive Medicine

IS - 5-6

ER -

Predictors of reported influenza vaccination in HIV-infected women in the United States, 2006-2007 and 2007-2008 seasons

Abstract

Keywords

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