Predictors of quality of life in type 2 diabetes patients with schizophrenia, major mood disorder, and without mental illness

Faith Dickerson, Karen Wohlheiter, Deborah Medoff, Lijuan Fang, Julie Kreyenbuhl, Richard Goldberg, Clayton Brown, Lisa Dixon

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: The aim of the current study is to compare the predictors of health-related quality of life in individuals with schizophrenia, major mood disorder, and no mental illness, all with type 2 diabetes. Methods: A total of 100 individuals with schizophrenia, 101 with a major mood disorder, and 99 without mental illness, all with type 2 diabetes, rated their health-related quality of life on the Medical Outcomes Survey, Short Form-12; physical and mental composite scores (PCS and MCS) were calculated. We performed a hierarchical multiple regression on PCS and MCS in each sample starting with a basic set of predictors and then adding diabetesrelated variables. We compared the regression weights and incremental variance explained within each group. Results: The number of co-occurring medical conditions was significantly associated with lower PCS in all three groups and with lower MCS in the no mental illness group. Diabetes-related variables added significant incremental variance to the prediction of PCS in the no mental illness group but not in either psychiatric group. Conclusions: For persons with diabetes and mental illness, as well as with no mental illness, additional medical conditions exert a strong effect on physical well-being. The impact on quality of life of diabetes-related factors may be lower in persons with diabetes and serious mental illness compared to those with diabetes and no mental illness.

Original languageEnglish (US)
Pages (from-to)1419-1425
Number of pages7
JournalQuality of Life Research
Volume20
Issue number9
DOIs
StatePublished - 2011
Externally publishedYes

Keywords

  • Diabetes
  • Mood disorders
  • Quality of life
  • Schizophrenia

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Medicine(all)

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