Predictive value of the Eustachian Tube Dysfunction Questionnaire-7 for identifying obstructive Eustachian tube dysfunction: A systematic review

Nicholas S. Andresen, Jeffrey D. Sharon, Carrie L. Nieman, Stella M. Seal, Bryan K. Ward

Research output: Contribution to journalReview articlepeer-review

Abstract

Objective: To perform a systematic review to determine if a total score of ≥14.5 (mean score ≥ 2.1) on the ETDQ-7 accurately identifies patients with obstructive Eustachian tube dysfunction (OETD) on impedance tympanometry (peak compliance <0.2 mL or middle ear pressure of −100 daPa) or other objective measures of OETD. Methods: A systematic review without a meta-analysis was performed of studies in four electronic databases (Pubmed, Embase, Web of Science, and Scopus) that used the ETDQ-7 and at least one objective measure of OETD. Results: Six-hundred and fifty-two studies were identified in the initial literature search. Abstracts from 337 studies were screened, followed by full-text review of 61 studies, and qualitative synthesis of 12 studies. Tympanometry was used as an objective measure in ten studies. Eight of the 12 included studies had patient cohort selection bias. Eight studies administered the ETDQ-7 in cohorts of patients with or without OETD, already confirmed on tympanometry, and found a sensitivity of 91%-100% and specificity of 67%-100%. Four studies administered the ETDQ-7 to patients who had not previously undergone objective testing and found a sensitivity of 49%-80% and specificity of 24%-78%. Conclusions: The ETDQ-7 is an important patient-reported outcome measure. However, based upon existing literature, the ETDQ-7 appears limited as a diagnostic tool for OETD or as an objective measure of Eustachian tube function.

Original languageEnglish (US)
Pages (from-to)844-851
Number of pages8
JournalLaryngoscope investigative otolaryngology
Volume6
Issue number4
DOIs
StatePublished - Aug 2021

Keywords

  • ETDQ-7
  • Eustachian Tube Dysfunction Questionnaire-7
  • Eustachian tube
  • Eustachian tube dysfunction
  • patient-reported outcomes

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology

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