Prediction of periventricular leukomalacia occurrence in neonates using a novel support vector machine classifier optimization method

Dieter Bender, Ali Jalali, Daniel J. Licht, C. Nataraj

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Prior work has documented that Support Vector Machine (SVM) classifiers can be powerful tools in predicting clinical outcomes of complex diseases such as Periventricular Leukomalacia (PVL). Our previous study showed that SVM performance can be improved significantly by optimizing the supervised training set used during the learning stage of the overall SVM algorithm. This study fully develops the initial idea using the reliable Leave-One-Out Cross-validation (LOOCV) technique. The work presented in this paper confirms previous results and improves the performance of the SVM even further. In addition, using the LOOCV technique, the computational time is decreased and the structure of the algorithm simplified, making this framework more feasible. Furthermore, we evaluate the performance of the resulting optimized SVM classifier on an unseen set of data. This demonstrates that the developed SVM algorithm outperforms normal SVM type classifiers without any loss of generalization.

Original languageEnglish (US)
Title of host publicationAdaptive and Intelligent Systems Control; Advances in Control Design Methods; Advances in Non-Linear and Optimal Control; Advances in Robotics; Advances in Wind Energy Systems; Aerospace Applications; Aerospace Power Optimization; Assistive Robotics; Automotive 2
Subtitle of host publicationHybrid Electric Vehicles; Automotive 3: Internal Combustion Engines; Automotive Engine Control; Battery Management; Bio Engineering Applications; Biomed and Neural Systems; Connected Vehicles; Control of Robotic Systems
PublisherAmerican Society of Mechanical Engineers
ISBN (Electronic)9780791857243
DOIs
StatePublished - 2015
Externally publishedYes
EventASME 2015 Dynamic Systems and Control Conference, DSCC 2015 - Columbus, United States
Duration: Oct 28 2015Oct 30 2015

Publication series

NameASME 2015 Dynamic Systems and Control Conference, DSCC 2015
Volume1

Conference

ConferenceASME 2015 Dynamic Systems and Control Conference, DSCC 2015
CountryUnited States
CityColumbus
Period10/28/1510/30/15

ASJC Scopus subject areas

  • Industrial and Manufacturing Engineering
  • Mechanical Engineering
  • Control and Systems Engineering

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