Prediction of occurrence of Periventricular Leukomalacia in neonates after heart surgery using a decision tree algorithm

Ali Jalali, C. Nataraj

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper is concerned with the prediction of the occurrence of Periventricular Leukomalacia (PVL), a form of white-matter brain injury, in neonates after heart surgery. The data which is collected over a period of 12 hours after the cardiac surgery contains measurements with different resolutions. The fact that data is collected at different time scales makes the modeling approach impractical, if not impossible. Hence, the decision tree classification technique has been selected for its capacity for discovering rules and novel associations in the data. It classifies groups based on reducing uncertainty in the classified data. From a physiological point of view we know that there are several regulatory mechanisms responsible for fluctuation of the hemodynamic variables at different time scales. To discover the most important active physiological components which might lead to the occurrence of PVL, we focus on the variation in the data in 1 min, 20 min and 2 hour periods. We calculate the energy of continuous wavelet transform coefficients of vital data at these time scales as a measure of variation in the different time frames. Results obtained from developing decision tree classifiers show that among all variations in all the variables, 2 hour and 20 minute variations in the heart rate and also 1 minute and 20 minute variation in Oxygen saturation are the most important parameters to predict PVL occurrence.

Original languageEnglish (US)
Title of host publicationASME 2012 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference, IDETC/CIE 2012
Pages217-222
Number of pages6
EditionPARTS A AND B
DOIs
StatePublished - 2012
Externally publishedYes
EventASME 2012 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference, IDETC/CIE 2012 - Chicago, IL, United States
Duration: Aug 12 2012Aug 12 2012

Publication series

NameProceedings of the ASME Design Engineering Technical Conference
NumberPARTS A AND B
Volume1

Conference

ConferenceASME 2012 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference, IDETC/CIE 2012
CountryUnited States
CityChicago, IL
Period8/12/128/12/12

ASJC Scopus subject areas

  • Modeling and Simulation
  • Mechanical Engineering
  • Computer Science Applications
  • Computer Graphics and Computer-Aided Design

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