Prediction of human errors by maladaptive changes in event-related brain networks

Tom Eichele, Stefan Debener, Vince Daniel Calhoun, Karsten Specht, Andreas K. Engel, Kenneth Hugdahl, D. Yves Von Cramon, Markus Ullsperger

Research output: Contribution to journalArticle

Abstract

Humans engaged in monotonous tasks are susceptible to occasional errors that may lead to serious consequences, but little is known about brain activity patterns preceding errors. Using functional MRI and applying independent component analysis followed by deconvolution of hemodynamic responses, we studied error preceding brain activity on a trial-by-trial basis. We found a set of brain regions in which the temporal evolution of activation predicted performance errors. These maladaptive brain activity changes started to evolve ≈30 sec before the error. In particular, a coincident decrease of deactivation in default mode regions of the brain, together with a decline of activation in regions associated with maintaining task effort, raised the probability of future errors. Our findings provide insights into the brain network dynamics preceding human performance errors and suggest that monitoring of the identified precursor states may help in avoiding human errors in critical real-world situations.

Original languageEnglish (US)
Pages (from-to)6173-6178
Number of pages6
JournalProceedings of the National Academy of Sciences of the United States of America
Volume105
Issue number16
DOIs
StatePublished - Apr 22 2008
Externally publishedYes

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Brain
Hemodynamics
Magnetic Resonance Imaging

Keywords

  • Deconvolution
  • Default mode
  • Frontal lobe
  • Performance monitoring

ASJC Scopus subject areas

  • Genetics
  • General

Cite this

Prediction of human errors by maladaptive changes in event-related brain networks. / Eichele, Tom; Debener, Stefan; Calhoun, Vince Daniel; Specht, Karsten; Engel, Andreas K.; Hugdahl, Kenneth; Von Cramon, D. Yves; Ullsperger, Markus.

In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, No. 16, 22.04.2008, p. 6173-6178.

Research output: Contribution to journalArticle

Eichele, Tom ; Debener, Stefan ; Calhoun, Vince Daniel ; Specht, Karsten ; Engel, Andreas K. ; Hugdahl, Kenneth ; Von Cramon, D. Yves ; Ullsperger, Markus. / Prediction of human errors by maladaptive changes in event-related brain networks. In: Proceedings of the National Academy of Sciences of the United States of America. 2008 ; Vol. 105, No. 16. pp. 6173-6178.
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