Prediction and prevention of autoimmune disease in the 21st Century: A review and preview

Noel R. Rose

Research output: Contribution to journalReview articlepeer-review

Abstract

Autoimmune diseases represent a family of at least 80 illnesses that share a common pathogenesis: an immune-mediated attack on the body's own organs. Collectively, autoimmune diseases affect some 20 million Americans, predominantly women. Many of these diseases are increasing in frequency in industrialized countries. Treatment of autoimmune diseases improved greatly during the second half of the 20th century but has been hampered because the diseases often progress before a clinical diagnosis is possible. Research in the 21st century is focusing on prospective prediction using the tools of systems biology.

Original languageEnglish (US)
Pages (from-to)403-406
Number of pages4
JournalAmerican journal of epidemiology
Volume183
Issue number5
DOIs
StatePublished - Mar 1 2016

Keywords

  • autoantibodies
  • autoimmune disease
  • biomarkers
  • major histocompatibility complex
  • prediction

ASJC Scopus subject areas

  • Epidemiology

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