TY - JOUR
T1 - Predicting abnormal coagulation in ischemic stroke
T2 - Reducing delay in rt-PA use
AU - Gottesman, Rebecca F.
AU - Alt, Janice
AU - Wityk, Robert J.
AU - Llinas, Rafael H.
PY - 2006/11
Y1 - 2006/11
N2 - Normal prothrombin time (PT) and partial thromboplastin time (PTT) are recommended for administration of recombinant tissue-plasminogen activator (rt-PA) in stroke, but waiting for results can delay use. We examined the charts of 365 stroke patients to assess predetermined risk factors associated with elevated PT/PTT. Elevated PT/PTT can be predicted in patients taking warfarin or heparin/heparinoid or on hemodialysis, according to emergency department triage, with 100% sensitivity and 94.7% specificity. These results could be applied to rt-PA candidates and reduce potential delays.
AB - Normal prothrombin time (PT) and partial thromboplastin time (PTT) are recommended for administration of recombinant tissue-plasminogen activator (rt-PA) in stroke, but waiting for results can delay use. We examined the charts of 365 stroke patients to assess predetermined risk factors associated with elevated PT/PTT. Elevated PT/PTT can be predicted in patients taking warfarin or heparin/heparinoid or on hemodialysis, according to emergency department triage, with 100% sensitivity and 94.7% specificity. These results could be applied to rt-PA candidates and reduce potential delays.
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U2 - 10.1212/01.wnl.0000244493.13898.5b
DO - 10.1212/01.wnl.0000244493.13898.5b
M3 - Article
C2 - 17101901
AN - SCOPUS:33751000747
SN - 0028-3878
VL - 67
SP - 1665
EP - 1667
JO - Neurology
JF - Neurology
IS - 9
ER -