Precursors of ovarian cancer in the fallopian tube: Serous tubal intraepithelial carcinoma - An update

Felix Zeppernick, Ivo Meinhold-Heerlein, Ie Ming Shih

Research output: Contribution to journalArticlepeer-review

Abstract

Ovarian tumors comprise a wide variety of entities. The largest group, epithelial ovarian carcinoma, can be classified into two main groups, type I and type II tumors. Recent advances in the understanding of ovarian cancer development have resulted in the finding of 'serous tubal intraepithelial carcinoma', which is believed to represent the precursor lesion in high-grade serous ovarian carcinoma. In this review, lines of evidence for this are discussed and possible future implications for clinical and research settings are outlined.

Original languageEnglish (US)
Pages (from-to)6-11
Number of pages6
JournalJournal of Obstetrics and Gynaecology Research
Volume41
Issue number1
DOIs
StatePublished - Jan 1 2015

Keywords

  • epithelial ovarian cancer
  • fallopian tube
  • high-grade serous carcinoma
  • precursor
  • serous tubal intraepithelial carcinoma

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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