Precursors of ovarian cancer in the fallopian tube: Serous tubal intraepithelial carcinoma - An update

Felix Zeppernick; Ivo Meinhold-Heerlein; Ie Ming Shih

doi:10.1111/jog.12550

Precursors of ovarian cancer in the fallopian tube: Serous tubal intraepithelial carcinoma - An update

Felix Zeppernick, Ivo Meinhold-Heerlein, Ie Ming Shih

School of Medicine

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

Ovarian tumors comprise a wide variety of entities. The largest group, epithelial ovarian carcinoma, can be classified into two main groups, type I and type II tumors. Recent advances in the understanding of ovarian cancer development have resulted in the finding of 'serous tubal intraepithelial carcinoma', which is believed to represent the precursor lesion in high-grade serous ovarian carcinoma. In this review, lines of evidence for this are discussed and possible future implications for clinical and research settings are outlined.

Original language	English (US)
Pages (from-to)	6-11
Number of pages	6
Journal	Journal of Obstetrics and Gynaecology Research
Volume	41
Issue number	1
DOIs	https://doi.org/10.1111/jog.12550
State	Published - Jan 1 2015

Keywords

epithelial ovarian cancer
fallopian tube
high-grade serous carcinoma
precursor
serous tubal intraepithelial carcinoma

ASJC Scopus subject areas

Obstetrics and Gynecology

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10.1111/jog.12550

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abstract = "Ovarian tumors comprise a wide variety of entities. The largest group, epithelial ovarian carcinoma, can be classified into two main groups, type I and type II tumors. Recent advances in the understanding of ovarian cancer development have resulted in the finding of 'serous tubal intraepithelial carcinoma', which is believed to represent the precursor lesion in high-grade serous ovarian carcinoma. In this review, lines of evidence for this are discussed and possible future implications for clinical and research settings are outlined.",

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AB - Ovarian tumors comprise a wide variety of entities. The largest group, epithelial ovarian carcinoma, can be classified into two main groups, type I and type II tumors. Recent advances in the understanding of ovarian cancer development have resulted in the finding of 'serous tubal intraepithelial carcinoma', which is believed to represent the precursor lesion in high-grade serous ovarian carcinoma. In this review, lines of evidence for this are discussed and possible future implications for clinical and research settings are outlined.

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Precursors of ovarian cancer in the fallopian tube: Serous tubal intraepithelial carcinoma - An update

Abstract

Keywords

ASJC Scopus subject areas

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