Precocious puberty in a boy with hepatoma and circulating gonadotropin

W. Hung, R. M. Blizzard, C. J. Migeon, A. M. Camacho, W. L. Nyhan

Research output: Contribution to journalArticle

Abstract

Sexual precocity resulting from circulating gonadotropin is reported in a 2-year-old child with hepatoblastoma. Following removal of the tumor the sexual precocity regressed and the gonadotropin in the serum disappeared. The patient eventually succumbed to his disease as have the other four similar patients that have been reported upon. This unusual cause of sexual precocity must be considered in the differential diagnosis of isosexual precocity. The clinical signs and symptoms, and the chemical abnormalities that occur in patients of this type, are discussed.

Original languageEnglish (US)
Pages (from-to)895-903
Number of pages9
JournalJournal of Pediatrics
Volume63
Issue number5
StatePublished - Nov 1963

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Precocious Puberty
Gonadotropins
Hepatocellular Carcinoma
Hepatoblastoma
Signs and Symptoms
Differential Diagnosis
Serum
Sexual precocity
Neoplasms

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Hung, W., Blizzard, R. M., Migeon, C. J., Camacho, A. M., & Nyhan, W. L. (1963). Precocious puberty in a boy with hepatoma and circulating gonadotropin. Journal of Pediatrics, 63(5), 895-903.

Precocious puberty in a boy with hepatoma and circulating gonadotropin. / Hung, W.; Blizzard, R. M.; Migeon, C. J.; Camacho, A. M.; Nyhan, W. L.

In: Journal of Pediatrics, Vol. 63, No. 5, 11.1963, p. 895-903.

Research output: Contribution to journalArticle

Hung, W, Blizzard, RM, Migeon, CJ, Camacho, AM & Nyhan, WL 1963, 'Precocious puberty in a boy with hepatoma and circulating gonadotropin', Journal of Pediatrics, vol. 63, no. 5, pp. 895-903.
Hung W, Blizzard RM, Migeon CJ, Camacho AM, Nyhan WL. Precocious puberty in a boy with hepatoma and circulating gonadotropin. Journal of Pediatrics. 1963 Nov;63(5):895-903.
Hung, W. ; Blizzard, R. M. ; Migeon, C. J. ; Camacho, A. M. ; Nyhan, W. L. / Precocious puberty in a boy with hepatoma and circulating gonadotropin. In: Journal of Pediatrics. 1963 ; Vol. 63, No. 5. pp. 895-903.
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