Sexual precocity resulting from circulating gonadotropin is reported in a 2-year-old child with hepatoblastoma. Following removal of the tumor the sexual precocity regressed and the gonadotropin in the serum disappeared. The patient eventually succumbed to his disease as have the other four similar patients that have been reported upon. This unusual cause of sexual precocity must be considered in the differential diagnosis of isosexual precocity. The clinical signs and symptoms, and the chemical abnormalities that occur in patients of this type, are discussed.
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health