Preclinical evaluation of an MRI-compatible pneumatic robot for angulated needle placement in transperineal prostate interventions

Junichi Tokuda, Sang Eun Song, Gregory S. Fischer, Iulian I. Iordachita, Reza Seifabadi, Nathan B. Cho, Kemal Tuncali, Gabor Fichtinger, Clare M. Tempany, Nobuhiko Hata

Research output: Contribution to journalArticle

Abstract

Purpose To evaluate the targeting accuracy of a small profile MRI-compatible pneumatic robot for needle placement that can angulate a needle insertion path into a large accessible target volume. Methods We extended our MRI-compatible pneumatic robot for needle placement to utilize its four degrees-of-freedom (4-DOF) mechanism with two parallel triangular structures and support transperineal prostate biopsies in a closed-bore magnetic resonance imaging (MRI) scanner. The robot is designed to guide a needle toward a lesion so that a radiologist can manually insert it in the bore. The robot is integrated with navigation software that allows an operator to plan angulated needle insertion by selecting a target and an entry point. The targeting error was evaluated while the angle between the needle insertion path and the static magnetic field was between -5.7̊ and 5.7̊ horizontally and between -5.7̊ and 4.3̊ vertically in the MRI scanner after sterilizing and draping the device. Results The robot positioned the needle for angulated insertion as specified on the navigation software with overall targeting error of 0.8 ± 0.5mm along the horizontal axis and 0.8 ± 0.8mm along the vertical axis. The two-dimensional root-mean-square targeting error on the axial slices as containing the targets was 1.4mm. Conclusions Our preclinical evaluation demonstrated that the MRI-compatible pneumatic robot for needle placement with the capability to angulate the needle insertion path provides targeting accuracy feasible for clinical MRI-guided prostate interventions. The clinical feasibility has to be established in a clinical study.

Original languageEnglish (US)
Pages (from-to)949-957
Number of pages9
JournalInternational journal of computer assisted radiology and surgery
Volume7
Issue number6
DOIs
StatePublished - Nov 2012
Externally publishedYes

Fingerprint

Magnetic resonance
Needles
Pneumatics
Prostate
Magnetic Resonance Imaging
Robots
Imaging techniques
Navigation
Software
Biopsy
Magnetic Fields
Magnetic fields
Equipment and Supplies

Keywords

  • Biopsy
  • Brachytherapy
  • Medical robotics
  • MRI-guided therapy
  • Prostate cancer

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Health Informatics
  • Surgery

Cite this

Preclinical evaluation of an MRI-compatible pneumatic robot for angulated needle placement in transperineal prostate interventions. / Tokuda, Junichi; Song, Sang Eun; Fischer, Gregory S.; Iordachita, Iulian I.; Seifabadi, Reza; Cho, Nathan B.; Tuncali, Kemal; Fichtinger, Gabor; Tempany, Clare M.; Hata, Nobuhiko.

In: International journal of computer assisted radiology and surgery, Vol. 7, No. 6, 11.2012, p. 949-957.

Research output: Contribution to journalArticle

Tokuda, J, Song, SE, Fischer, GS, Iordachita, II, Seifabadi, R, Cho, NB, Tuncali, K, Fichtinger, G, Tempany, CM & Hata, N 2012, 'Preclinical evaluation of an MRI-compatible pneumatic robot for angulated needle placement in transperineal prostate interventions', International journal of computer assisted radiology and surgery, vol. 7, no. 6, pp. 949-957. https://doi.org/10.1007/s11548-012-0750-1
Tokuda, Junichi ; Song, Sang Eun ; Fischer, Gregory S. ; Iordachita, Iulian I. ; Seifabadi, Reza ; Cho, Nathan B. ; Tuncali, Kemal ; Fichtinger, Gabor ; Tempany, Clare M. ; Hata, Nobuhiko. / Preclinical evaluation of an MRI-compatible pneumatic robot for angulated needle placement in transperineal prostate interventions. In: International journal of computer assisted radiology and surgery. 2012 ; Vol. 7, No. 6. pp. 949-957.
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AU - Seifabadi, Reza

AU - Cho, Nathan B.

AU - Tuncali, Kemal

AU - Fichtinger, Gabor

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AB - Purpose To evaluate the targeting accuracy of a small profile MRI-compatible pneumatic robot for needle placement that can angulate a needle insertion path into a large accessible target volume. Methods We extended our MRI-compatible pneumatic robot for needle placement to utilize its four degrees-of-freedom (4-DOF) mechanism with two parallel triangular structures and support transperineal prostate biopsies in a closed-bore magnetic resonance imaging (MRI) scanner. The robot is designed to guide a needle toward a lesion so that a radiologist can manually insert it in the bore. The robot is integrated with navigation software that allows an operator to plan angulated needle insertion by selecting a target and an entry point. The targeting error was evaluated while the angle between the needle insertion path and the static magnetic field was between -5.7̊ and 5.7̊ horizontally and between -5.7̊ and 4.3̊ vertically in the MRI scanner after sterilizing and draping the device. Results The robot positioned the needle for angulated insertion as specified on the navigation software with overall targeting error of 0.8 ± 0.5mm along the horizontal axis and 0.8 ± 0.8mm along the vertical axis. The two-dimensional root-mean-square targeting error on the axial slices as containing the targets was 1.4mm. Conclusions Our preclinical evaluation demonstrated that the MRI-compatible pneumatic robot for needle placement with the capability to angulate the needle insertion path provides targeting accuracy feasible for clinical MRI-guided prostate interventions. The clinical feasibility has to be established in a clinical study.

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