TY - GEN
T1 - Precision radiotherapy for small animal research
AU - Matinfar, Mohammad
AU - Iordachita, Iulian
AU - Ford, Eric
AU - Wong, John
AU - Kazanzides, Peter
N1 - Funding Information:
This work was supported by NIH R01 CA108449.
PY - 2008
Y1 - 2008
N2 - Preclinical research using well characterized small animal models has provided tremendous benefits to medical research, enabling low cost, large scale trials with high statistical significance of observed effects. The goal of the Small Animal Radiation Research Platform (SARRP) is to make those models available for the development and evaluation of novel radiation therapies. SARRP demonstrates the capabilities of delivering high resolution, sub-millimeter, optimally planned conformal radiation with on-board cone-beam CT (CBCT) guidance. The system requires accurate calibration of the x-ray beam for both imaging and radiation treatment. In this paper, we present a novel technique using an x-ray camera for calibration of the treatment beam. This technique does not require precise positioning or calibration of the x-ray camera.
AB - Preclinical research using well characterized small animal models has provided tremendous benefits to medical research, enabling low cost, large scale trials with high statistical significance of observed effects. The goal of the Small Animal Radiation Research Platform (SARRP) is to make those models available for the development and evaluation of novel radiation therapies. SARRP demonstrates the capabilities of delivering high resolution, sub-millimeter, optimally planned conformal radiation with on-board cone-beam CT (CBCT) guidance. The system requires accurate calibration of the x-ray beam for both imaging and radiation treatment. In this paper, we present a novel technique using an x-ray camera for calibration of the treatment beam. This technique does not require precise positioning or calibration of the x-ray camera.
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U2 - 10.1007/978-3-540-85990-1_74
DO - 10.1007/978-3-540-85990-1_74
M3 - Conference contribution
C2 - 18982656
AN - SCOPUS:79551683179
SN - 3540859896
SN - 9783540859895
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 619
EP - 626
BT - Medical Image Computing and Computer-Assisted Intervention - MICCAI 2008 - 11th International Conference, Proceedings
PB - Springer Verlag
T2 - 11th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2008
Y2 - 6 September 2008 through 10 September 2008
ER -