Precision of marker heterozygosity estimates

Y. Y. Shugart

Research output: Contribution to journalArticlepeer-review


Sample sizes may greatly affect the accuracy of estimates of marker heterozygosities. Therefore, indicating the precision of these estimates is strongly recommended. A computer program HETMAX was written and used to obtain unbiased estimates of heterozygosity, their standard errors and unit support intervals, based on a subset of GAW9 data. The accuracy of the estimates and the associated sample sizes are presented.

Original languageEnglish (US)
Pages (from-to)671-674
Number of pages4
JournalGenetic Epidemiology
Issue number6
StatePublished - 1995
Externally publishedYes


  • heterozygosity
  • sample size
  • standard error
  • support interval

ASJC Scopus subject areas

  • Genetics(clinical)
  • Epidemiology


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