Abstract
Sample sizes may greatly affect the accuracy of estimates of marker heterozygosities. Therefore, indicating the precision of these estimates is strongly recommended. A computer program HETMAX was written and used to obtain unbiased estimates of heterozygosity, their standard errors and unit support intervals, based on a subset of GAW9 data. The accuracy of the estimates and the associated sample sizes are presented.
Original language | English (US) |
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Pages (from-to) | 671-674 |
Number of pages | 4 |
Journal | Genetic Epidemiology |
Volume | 12 |
Issue number | 6 |
DOIs | |
State | Published - 1995 |
Externally published | Yes |
Keywords
- heterozygosity
- sample size
- standard error
- support interval
ASJC Scopus subject areas
- Genetics(clinical)
- Epidemiology